Phospholipase D Activity Assay Kit
sufficient for 100 colorimetric or fluorometric tests
Manufacturer: Sigma Aldrich
Synonym(S): PLD Activity Assay Kit
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 KIT | MAK137-1-KIT | In Stock | ₹ 36,174.90 |
MAK137 - 1 KIT
In Stock
Quantity
1
Base Price: ₹ 36,174.90
GST (18%): ₹ 6,511.482
Total Price: ₹ 42,686.382
usage
sufficient for 100 colorimetric or fluorometric tests
detection method
colorimetricfluorometric
relevant disease(s)
cancer
storage temp.
−20°C
Gene Information
human ... PLD1(5337) , PLD2(5338) , PLD3(23646) , PLD4(122618) , PLD5(200150) , PLD6(201164) mouse ... PLD1(18805) , PLD2(18806) , PLD3(18807) , PLD4(104759) , PLD5(319455) , PLD6(194908) rat ... PLD1(25096) , PLD2(25097) , PLD3(361527) , PLD4(362792) , PLD5(289270) , PLD6(287366)
Related Products
Description
- General description: Phospholipase D (PLD) catalyzes the hydrolysis of the phosphodiester bond of glycerophospholipids to generate phosphatidic acid and choline. It is ubiquitously expressed and is implicated in immune function and cancer inhibition.[1] Abnormalities in PLD expression have been associated with human cancers such as breast, renal, gastric and colorectal cancer.[2]
- Application: Phospholipase D (PLD) Activity Assay Kit has been used to measure PLD activity in the liver and lysosomal fractions of the mice liver.[3]
- Features and Benefits: Compatible with high-throughput handling systems.
- Suitability: Suitable for the quantitative determination of phospholipase D activity and evaluation of drug effects on phospholipase D metabolism.
- Principle: In this assay, PLD hydrolyzes phosphatidylcholine to choline, which is determined using choline oxidase resulting in a colorimetric (570 nm)/fluorometric (λex = 530/λem = 585 nm) product, proportional to the PLD activity in the sample. Unit definition: one unit of PLD catalyzes the formation of 1 mmole choline per minute under the assay conditions (pH 7.4).
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 3 - Resp. Sens. 1
WGK
WGK 3
Flash Point(F)
188.6 °F
Flash Point(C)
87 °C
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usage: sufficient for 100 colorimetric or fluorometric tests
detection method: colorimetricfluorometric
relevant disease(s): cancer
storage temp.: −20°C
Gene Information: human ... PLD1(5337) , PLD2(5338) , PLD3(23646) , PLD4(122618) , PLD5(200150) , PLD6(201164) mouse ... PLD1(18805) , PLD2(18806) , PLD3(18807) , PLD4(104759) , PLD5(319455) , PLD6(194908) rat ... PLD1(25096) , PLD2(25097) , PLD3(361527) , PLD4(362792) , PLD5(289270) , PLD6(287366)
usage: sufficient for 200 fluorometric tests
detection method: fluorometric
relevant disease(s): cancer; immunological diseases
storage temp.: −20°C
Gene Information: __
usage: sufficient for 200 colorimetric tests
detection method: colorimetric
relevant disease(s): neurological disorders
storage temp.: −20°C
Gene Information: __