Description

• General description: β-Nicotinamide adenine dinucleotide (NAD) is an electron carrier[1] and a cofactor. It is ubiquitously found in the living system. NAD+ contains an adenylic acid and a nicotinamide-5′-ribonucleotide group linked together by a pyrophosphate moiety. In NAD+ complexes, the enzyme-cofactor interactions are highly conserved.[2]
• Application: β-Nicotinamide adenine dinucleotide hydrate has been used:to measure adenosine triphosphate (ATP) synthesis rates (kinetics measurements)[3]in the reaction buffer for pyruvate kinase (PK) activity assay[4]as a component of master mix for a high throughput screening[5]
• Biochem/physiol Actions: β-Nicotinamide adenine dinucleotide (NAD) cycles between the oxidized (NAD+) and reduced (NADH) forms to maintain a redox balance necessary for continued cell growth.[6] It significantly participates in enzyme-catalyzed oxido-reduction processes[2] and many genetic processes. It is also involved in microbial catabolism.[6]
• Packaging: Packaged by solid weight.
• Other Notes: Crystalline NAD contains less than 0.1% (w/w) residual organic solvent, is less hygroscopic and electrostatic, and is more stable at ambient temperatures than amorphous NAD.