Nonactin
from Streptomyces griseus, ≥98.0% (Total homologs, HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 6833-84-7
Synonym(S): Ammonium ionophore I, Ammonium ionophore
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 MG | N2286-10-MG | In Stock | ₹ 15,468.93 |
| 100 MG | N2286-100-MG | In Stock | ₹ 73,090.40 |
N2286 - 10 MG
In Stock
Quantity
1
Base Price: ₹ 15,468.93
GST (18%): ₹ 2,784.407
Total Price: ₹ 18,253.337
biological source
Streptomyces griseus
Quality Level
300
description
Natural macrotetrolide, may contain homologues (like monactin and dinactin)
Assay
≥98.0% (Total homologs, HPLC)
form
powder
solubility
chloroform: soluble 10 mg/mL
antibiotic activity spectrum
Gram-positive bacteria
Mode of action
DNA synthesis | interferescell membrane | interferes
storage temp.
2-8°C
SMILES string
C[C@H]1C[C@@H]2CC[C@@H](O2)[C@@H](C)C(=O)O[C@H](C)C[C@H]3CC[C@H](O3)[C@H](C)C(=O)O[C@@H](C)C[C@@H]4CC[C@@H](O4)[C@@H](C)C(=O)O[C@H](C)C[C@H]5CC[C@H](O5)[C@H](C)C(=O)O1
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Medchemexpress LLC HY-N6790 1mg Medchemexpress, Nonactin CAS:6833-84-7 Purity:>98% | Medchemexpress LLC | ₹ 14,823.27 | |
 | Sigma Aldrich Fine Chemicals Biosciences Nonactin from Streptomyces griseus, >=98% (function tested, HPLC) | 6833-84-7 | 100MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 1,15,095.31 | |
| | eMolecules Medchem Express / Nonactin / 1mg / 495800973 / HY-N6790 / / 6833-84-7 / MFCD03267283 / 736.940 / C40H64O12 | eMolecules | ₹ 20,780.81 | |
 | 6833-84-7 | Nonactin | A2B Chem | ₹ 3,850.20 - ₹ 14,630.76 |
Related Products
Description
- General description: Chemical structure: macrolide
- Application: Nonactin is a macrotetrolide that forms complexes with alkali cations, such as potassium and sodium. Nonactin has been reported to inhibit the processing of cytoplasmic precursor proteins destined for the mitochondria. Nonactin is an uncoupler of oxidative phosphorylation [1].
- Biochem/physiol Actions: Nonactin is used as a neutral lipid membrane soluble ammonium (and potassium) ionophore, and to inhibit surface expression of certain heat shock proteins (HSP60) [2][3].
- Other Notes: Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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biological source: Streptomyces griseus
Quality Level: 300
description: Natural macrotetrolide, may contain homologues (like monactin and dinactin)
Assay: ≥98.0% (Total homologs, HPLC)
form: powder
solubility: chloroform: soluble 10 mg/mL
antibiotic activity spectrum: Gram-positive bacteria
Mode of action: DNA synthesis | interferescell membrane | interferes
storage temp.: 2-8°C
SMILES string: C[C@H]1C[C@@H]2CC[C@@H](O2)[C@@H](C)C(=O)O[C@H](C)C[C@H]3CC[C@H](O3)[C@H](C)C(=O)O[C@@H](C)C[C@@H]4CC[C@@H](O4)[C@@H](C)C(=O)O[C@H](C)C[C@H]5CC[C@H](O5)[C@H](C)C(=O)O1
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