N1628
Novobiocin sodium salt
≥90% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 1476-53-5
Synonym(S): Albamycin, Albamycin Sodium, Cathomycin sodium
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 G | N1628-1-G | In Stock | ₹ 6,310.98 |
| 5 G | N1628-5-G | In Stock | ₹ 12,492.05 |
| 25 G | N1628-25-G | In Stock | ₹ 59,028.73 |
| 100 G | N1628-100-G | In Stock | ₹ 1,25,158.65 |
N1628 - 1 G
In Stock
Quantity
1
Base Price: ₹ 6,310.98
GST (18%): ₹ 1,135.976
Total Price: ₹ 7,446.956
biological source
(STREPTOMYCES NIVEUS)
Quality Level
200
Assay
≥90% (HPLC)
form
powder
storage condition
(Tightly closed. Dry. )
color
white to yellow
antibiotic activity spectrum
Gram-positive bacteria
Mode of action
DNA synthesis | interferesenzyme | inhibits
storage temp.
2-8°C
SMILES string
[Na+].CO[C@@H]1[C@@H](OC(N)=O)[C@@H](O)[C@H](Oc2ccc3C([O-])=C(NC(=O)c4ccc(O)c(C\C=C(\C)C)c4)C(=O)Oc3c2C)OC1(C)C
Other Options
Related Products
Description
- General description: Novobiocin sodium salt is an antibiotic derived from soil bacteria. Novobiocin inhibits the action of bacterial DNA gyrase and belongs to a class of compounds called coumarin antibiotics. Coumarins are heterocyclic compounds with a wide range of biological activity, including antibacterial, anticoagulant, antioxidant, anti-inflammatory, antiviral, antitumor, and enzyme inhibitory effects.
- Application: Novobiocin Sodium Salt, an inhibitor of Hsp90, can be used:in the research heat shock protein inhibition and to produce positively supercoiled plasmid DNA[1]in the research on the efficacy of probiotics[2][3]in the research on the efficacy of human monocytes and dendritic cells for T-cell replication[4]
- Biochem/physiol Actions: Novobiocin inhibits DNA synthesis by inhibiting the GyrB subunit of the Topoisomerase enzyme involved in energy transduction. Novobiocin acts as a competitive inhibitor of the ATPase reaction catalysed by GyrB[1].
- Features and Benefits: High quality antibiotic suitable for mulitple research applications
- Storage and Stability: Stored in frozen aliquots, Keep container tightly closed in a dry and well-ventilated place. Light sensitive
- Other Notes: For additional information on our range of Biochemicals, please complete this form.
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
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biological source: (STREPTOMYCES NIVEUS)
Quality Level: 200
Assay: ≥90% (HPLC)
form: powder
storage condition: (Tightly closed. Dry. )
color: white to yellow
antibiotic activity spectrum: Gram-positive bacteria
Mode of action: DNA synthesis | interferesenzyme | inhibits
storage temp.: 2-8°C
SMILES string: [Na+].CO[C@@H]1[C@@H](OC(N)=O)[C@@H](O)[C@H](Oc2ccc3C([O-])=C(NC(=O)c4ccc(O)c(C\C=C(\C)C)c4)C(=O)Oc3c2C)OC1(C)C
biological source:
(STREPTOMYCES NIVEUS)
Quality Level:
200
Assay:
≥90% (HPLC)
form:
powder
storage condition:
(Tightly closed. Dry. )
color:
white to yellow
antibiotic activity spectrum:
Gram-positive bacteria
Mode of action:
DNA synthesis | interferesenzyme | inhibits
storage temp.:
2-8°C
SMILES string:
[Na+].CO[C@@H]1[C@@H](OC(N)=O)[C@@H](O)[C@H](Oc2ccc3C([O-])=C(NC(=O)c4ccc(O)c(C\C=C(\C)C)c4)C(=O)Oc3c2C)OC1(C)C
biological source: __
Quality Level: 300
Assay: ≥93% (HPLC)≥93% (spectrophotometric assay)
form: powder
storage condition: __
color: __
antibiotic activity spectrum: __
Mode of action: __
storage temp.: −20°C
SMILES string: [Na+].[Na+].[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@H]2O[C@@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](OP([O-])([O-])=O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@H](O)[C@@H]2O
biological source:
__
Quality Level:
300
Assay:
≥93% (HPLC)≥93% (spectrophotometric assay)
form:
powder
storage condition:
__
color:
__
antibiotic activity spectrum:
__
Mode of action:
__
storage temp.:
−20°C
SMILES string:
[Na+].[Na+].[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@H]2O[C@@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](OP([O-])([O-])=O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@H](O)[C@@H]2O
biological source: __
Quality Level: 200
Assay: ≥99%
form: crystalline powder
storage condition: __
color: white
antibiotic activity spectrum: __
Mode of action: __
storage temp.: −20°C
SMILES string: NC1=NC=NC2=C1N=CN2.O[C@@H]3[C@@H](COP(O)(OP(OC[C@@H](O4)[C@@H](O)[C@@H](O)[C@H]4[N+]5=CC=CC(C(N)=O)=C5)([O-])=O)=O)OC[C@@H]3O
biological source:
__
Quality Level:
200
Assay:
≥99%
form:
crystalline powder
storage condition:
__
color:
white
antibiotic activity spectrum:
__
Mode of action:
__
storage temp.:
−20°C
SMILES string:
NC1=NC=NC2=C1N=CN2.O[C@@H]3[C@@H](COP(O)(OP(OC[C@@H](O4)[C@@H](O)[C@@H](O)[C@H]4[N+]5=CC=CC(C(N)=O)=C5)([O-])=O)=O)OC[C@@H]3O
biological source: __
Quality Level: 200
Assay: __
form: suspension
storage condition: __
color: yellow
antibiotic activity spectrum: fungiyeast
Mode of action: cell membrane | interferes
storage temp.: __
SMILES string: __
biological source:
__
Quality Level:
200
Assay:
__
form:
suspension
storage condition:
__
color:
yellow
antibiotic activity spectrum:
fungiyeast
Mode of action:
cell membrane | interferes
storage temp.:
__
SMILES string:
__