SMB00314
Coptisine Chloride
≥98% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 6020-18-4
Synonym(S): Coptisine chloride, Bis(methylenedioxy)protoberberine chloride, Coptisin Chloride
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 25 MG | SMB00314-25-MG | In Stock | ₹ 40,409.73 |
SMB00314 - 25 MG
In Stock
Quantity
1
Base Price: ₹ 40,409.73
GST (18%): ₹ 7,273.751
Total Price: ₹ 47,683.481
Quality Level
200
Assay
≥98% (HPLC)
form
powder
application(s)
metabolomicsvitamins, nutraceuticals, and natural products
storage temp.
−20°C
SMILES string
C1(OCO2)=C2C=C(CC[N+]3=C4C=C5C(C(OCO6)=C6C=C5)=C3)C4=C1.[Cl-]
InChI
1S/C19H14NO4.ClH/c1-2-16-19(24-10-21-16)14-8-20-4-3-12-6-17-18(23-9-22-17)7-13(12)15(20)5-11(1)14;/h1-2,5-8H,3-4,9-10H2;1H/q+1;/p-1
InChI key
LUXPUVKJHVUJAV-UHFFFAOYSA-M
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Medchemexpress LLC HY-N0736 5mg Medchemexpress, Coptisine (chloride) CAS:6020-18-4 Purity:>98% | Medchemexpress LLC | ₹ 6,737.85 | |
 | Bis[1,3]benzodioxolo[5,6-a:4',5'-g]quinolizinium, 6,7-dihydro-, chloride | Aaron Chemicals LLC | ₹ 1,540.08 - ₹ 14,630.76 | |
 | 6020-18-4 | Bis[1,3]benzodioxolo[5,6-a:4',5'-g]quinolizinium, 6,7-dihydro-, chloride | A2B Chem | ₹ 9,326.04 - ₹ 74,009.40 |
Description
- General description: Coptisine chloride is a cytotoxic isoquinoline alkaloid.[1] It is the major bioactive compound of Coptis rhizome[2], and can also be found in different plants such as Chelidonium majus[3], Enantia chlorantha.[1] Coptisine is related to berberine[3] and has a similar structure to that of Jatrorrhizine.[1]
- Application: Coptisine Chloride has been used to study its binding interactions with single-stranded poly(A) using different absorbance and thermal melting spectroscopic experiments.[1] It may have been used as a standard to analyze Chelidonium majus L. extracted compounds using UV/VIS absorption spectroscopy.[3]
- Biochem/physiol Actions: Coptisine Chloride is a potent anti-malarial compound[2], which also exerts anti-cancer and anti-diabetic properties.[1] It elicits protective effects on gastric mucus membrane and is used as a traditional medicine against gastroenteric diseases.[1] Coptisine chloride also displays anti-microbial activities.[4]It has been analyzed as a cytotoxic agent in hepatoma and leukemic cells and is reported to block cell cycle progression.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
P260 - P264 - P271 - P284 - P304 + P340 + P310 - P403 + P233
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Show Difference
Quality Level: 200
Assay: ≥98% (HPLC)
form: powder
application(s): metabolomicsvitamins, nutraceuticals, and natural products
storage temp.: −20°C
SMILES string: C1(OCO2)=C2C=C(CC[N+]3=C4C=C5C(C(OCO6)=C6C=C5)=C3)C4=C1.[Cl-]
InChI: 1S/C19H14NO4.ClH/c1-2-16-19(24-10-21-16)14-8-20-4-3-12-6-17-18(23-9-22-17)7-13(12)15(20)5-11(1)14;/h1-2,5-8H,3-4,9-10H2;1H/q+1;/p-1
InChI key: LUXPUVKJHVUJAV-UHFFFAOYSA-M
Quality Level:
200
Assay:
≥98% (HPLC)
form:
powder
application(s):
metabolomicsvitamins, nutraceuticals, and natural products
storage temp.:
−20°C
SMILES string:
C1(OCO2)=C2C=C(CC[N+]3=C4C=C5C(C(OCO6)=C6C=C5)=C3)C4=C1.[Cl-]
InChI:
1S/C19H14NO4.ClH/c1-2-16-19(24-10-21-16)14-8-20-4-3-12-6-17-18(23-9-22-17)7-13(12)15(20)5-11(1)14;/h1-2,5-8H,3-4,9-10H2;1H/q+1;/p-1
InChI key:
LUXPUVKJHVUJAV-UHFFFAOYSA-M
Quality Level: 200
Assay: ≥98% (HPLC)
form: powder
application(s): metabolomicsvitamins, nutraceuticals, and natural products
storage temp.: −20°C
SMILES string: O[C@@H]1[C@@H](O)[C@H](OC/C=C/C2=CC=CC=C2)O[C@H](CO[C@H]3[C@H](O)[C@@H](O)[C@H](CO)O3)[C@H]1O
InChI: 1S/C20H28O10/c21-9-12-14(22)17(25)20(29-12)28-10-13-15(23)16(24)18(26)19(30-13)27-8-4-7-11-5-2-1-3-6-11/h1-7,12-26H,8-10H2/b7-4+/t12-,13+,14-,15+,16-,17+,18+,19+,20+/m0/s1
InChI key: IEBFEMIXXHIISM-YZOUKVLTSA-N
Quality Level:
200
Assay:
≥98% (HPLC)
form:
powder
application(s):
metabolomicsvitamins, nutraceuticals, and natural products
storage temp.:
−20°C
SMILES string:
O[C@@H]1[C@@H](O)[C@H](OC/C=C/C2=CC=CC=C2)O[C@H](CO[C@H]3[C@H](O)[C@@H](O)[C@H](CO)O3)[C@H]1O
InChI:
1S/C20H28O10/c21-9-12-14(22)17(25)20(29-12)28-10-13-15(23)16(24)18(26)19(30-13)27-8-4-7-11-5-2-1-3-6-11/h1-7,12-26H,8-10H2/b7-4+/t12-,13+,14-,15+,16-,17+,18+,19+,20+/m0/s1
InChI key:
IEBFEMIXXHIISM-YZOUKVLTSA-N
Quality Level: 200
Assay: ≥97% (HPLC)
form: powder
application(s): metabolomicsvitamins, nutraceuticals, and natural products
storage temp.: −20°C
SMILES string: CC(O[C@@]12[C@@]3([H])[C@H](OC)[C@]4([H])[C@](COC)(CN(C)[C@H]35)[C@H](O)C[C@H](OC)[C@@]45[C@]([H])(C[C@@H](OC)[C@@H]2O)[C@]1([H])C(OC(C6=CC=CC=C6)=O)O)=O
InChI: 1S/C32H45NO11/c1-16(34)44-32-22(29(38)43-28(37)17-10-8-7-9-11-17)18(12-19(40-4)27(32)36)31-21(41-5)13-20(35)30(15-39-3)14-33(2)26(31)23(32)24(42-6)25(30)31/h7-11,18-27,29,35-36,38H,12-15H2,1-6H3/t18-,19-,20-,21+,22-,23+,24+,25-,26?,27+,29?,30+,31+,32-/m1/s1
InChI key: IORXNCZGFBAKNU-IIEDEHCPSA-N
Quality Level:
200
Assay:
≥97% (HPLC)
form:
powder
application(s):
metabolomicsvitamins, nutraceuticals, and natural products
storage temp.:
−20°C
SMILES string:
CC(O[C@@]12[C@@]3([H])[C@H](OC)[C@]4([H])[C@](COC)(CN(C)[C@H]35)[C@H](O)C[C@H](OC)[C@@]45[C@]([H])(C[C@@H](OC)[C@@H]2O)[C@]1([H])C(OC(C6=CC=CC=C6)=O)O)=O
InChI:
1S/C32H45NO11/c1-16(34)44-32-22(29(38)43-28(37)17-10-8-7-9-11-17)18(12-19(40-4)27(32)36)31-21(41-5)13-20(35)30(15-39-3)14-33(2)26(31)23(32)24(42-6)25(30)31/h7-11,18-27,29,35-36,38H,12-15H2,1-6H3/t18-,19-,20-,21+,22-,23+,24+,25-,26?,27+,29?,30+,31+,32-/m1/s1
InChI key:
IORXNCZGFBAKNU-IIEDEHCPSA-N
Quality Level: 200
Assay: ≥98% (HPLC)
form: powder
application(s): metabolomicsvitamins, nutraceuticals, and natural products
storage temp.: __
SMILES string: OC1=CC=C([C@@H]2CC(C(C(O)=CC(O[C@@H]3O[C@H](CO[C@H]4[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O4)[C@@H](O)[C@H](O)[C@H]3O)=C5)=C5O2)=O)C=C1
InChI: 1S/C27H32O14/c1-10-20(31)22(33)24(35)26(38-10)37-9-18-21(32)23(34)25(36)27(41-18)39-13-6-14(29)19-15(30)8-16(40-17(19)7-13)11-2-4-12(28)5-3-11/h2-7,10,16,18,20-29,31-36H,8-9H2,1H3/t10-,16-,18+,20-,21+,22+,23-,24+,25+,26+,27+/m0/s1
InChI key: HXTFHSYLYXVTHC-AJHDJQPGSA-N
Quality Level:
200
Assay:
≥98% (HPLC)
form:
powder
application(s):
metabolomicsvitamins, nutraceuticals, and natural products
storage temp.:
__
SMILES string:
OC1=CC=C([C@@H]2CC(C(C(O)=CC(O[C@@H]3O[C@H](CO[C@H]4[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O4)[C@@H](O)[C@H](O)[C@H]3O)=C5)=C5O2)=O)C=C1
InChI:
1S/C27H32O14/c1-10-20(31)22(33)24(35)26(38-10)37-9-18-21(32)23(34)25(36)27(41-18)39-13-6-14(29)19-15(30)8-16(40-17(19)7-13)11-2-4-12(28)5-3-11/h2-7,10,16,18,20-29,31-36H,8-9H2,1H3/t10-,16-,18+,20-,21+,22+,23-,24+,25+,26+,27+/m0/s1
InChI key:
HXTFHSYLYXVTHC-AJHDJQPGSA-N