SMB00377

Magnoflorine

≥98% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 2141-09-5

Synonym(S): (6aS)-2,10-dimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-6-ium-1,11-diol

Select a Size

Pack Size SKU Availability Price
10 MG SMB00377-10-MG In Stock ₹ 16,510.00

SMB00377 - 10 MG

₹ 16,510.00

In Stock

Quantity

1

Base Price: ₹ 16,510.00

GST (18%): ₹ 2,971.80

Total Price: ₹ 19,481.80

Quality Level

200

Assay

≥98% (HPLC)

form

powder

application(s)

metabolomicsvitamins, nutraceuticals, and natural products

storage temp.

2-8°C

SMILES string

OC1=C(OC)C=C2CC[N+](C)(C)[C@@]3([H])CC4=CC=C(OC)C(O)=C4C1=C32

InChI

1S/C20H23NO4/c1-21(2)8-7-12-10-15(25-4)20(23)18-16(12)13(21)9-11-5-6-14(24-3)19(22)17(11)18/h5-6,10,13H,7-9H2,1-4H3,(H-,22,23)/p+1/t13-/m0/s1

InChI key

YLRXAIKMLINXQY-ZDUSSCGKSA-O

Other Options

Image Product Name Manufacturer Price Range
50-174-5255
Sigma Aldrich Fine Chemicals Biosciences Magnoflorine >=98% (HPLC) | 2141-09-5 | MFCD09031380 | 10MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 18,865.98
AR00BCOS
(+)-Magnoflorine iodide
Aaron Chemicals LLC ₹ 13,176.24 - ₹ 21,047.76
AF28560
2141-09-5 | (+)-MAGNOFLORINE IODIDE
A2B Chem ₹ 7,529.28 - ₹ 10,438.32

Description

  • General description: Magnoflorine is a secondary metabolite and an alkaloid with a quaternary aporphine configuration.[1] It can be found in roots, rhizomes, stems, barks, or seeds of many herbal plants such as Caulophyllum thalictroides (blue cohosh), Arisolochai bracteate[2], P. amurense, S. acutum[1], Tinospora crispa[3], Coptidis rhizome[4], etc. Magnoflorine constitutes approximately 65 % of the total alkaloids in roots and rhizomes of blue cohosh.[2] It is also known as thalictrine and escholine.[1]
  • Application: Magnoflorin has been used to test its contractile effects on isolated mouse uterine smooth muscle tissues[2] and on isolated strips of Mus musculus distal colon smooth muscle tissues.[5]
  • Biochem/physiol Actions: Magnoflorine possesses several biochemical and pharmacological properties such as antioxidant, anti-inflammatory, immunomodulatory, anti-diabetic, anti-fungal, cardiovascular protective, and neuropsychological.[1] It also acts as an α-tyrosinase inhibitor.[1] It helps to increase pro-inflammatory responses induced by lipopolysaccharide (LPS).[3] It exerts antitumor, anti-cancer activities by inhibiting gastric cancer progression gastric cancer cell xenograft mouse model.[4]

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H302 + H312 + H332

Precautionary Statements

P261 - P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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≥98% (HPLC)

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OC1=C(OC)C=C2CC[N+](C)(C)[C@@]3([H])CC4=CC=C(OC)C(O)=C4C1=C32

InChI:
1S/C20H23NO4/c1-21(2)8-7-12-10-15(25-4)20(23)18-16(12)13(21)9-11-5-6-14(24-3)19(22)17(11)18/h5-6,10,13H,7-9H2,1-4H3,(H-,22,23)/p+1/t13-/m0/s1

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YLRXAIKMLINXQY-ZDUSSCGKSA-O

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NC(C1=CC(CCC)=NC=C1)=S

InChI:
1S/C9H12N2S/c1-2-3-8-6-7(9(10)12)4-5-11-8/h4-6H,2-3H2,1H3,(H2,10,12)

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VRDIULHPQTYCLN-UHFFFAOYSA-N

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COc1cc(O)c(C\C=C(\C)C)c2OC(CC(=O)c12)c3ccc(O)cc3

InChI:
1S/C21H22O5/c1-12(2)4-9-15-16(23)10-19(25-3)20-17(24)11-18(26-21(15)20)13-5-7-14(22)8-6-13/h4-8,10,18,22-23H,9,11H2,1-3H3

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YKGCBLWILMDSAV-UHFFFAOYSA-N

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Sigma Aldrich

SMB00390

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SMILES string:
OC([C@]([C@@H](O)CO)([H])O1)=C(C1=O)O[C@H]([C@@H]([C@@H](O)[C@@H]2O)O)O[C@@H]2CO

InChI:
1S/C12H18O11/c13-1-3(15)9-8(19)10(11(20)22-9)23-12-7(18)6(17)5(16)4(2-14)21-12/h3-7,9,12-19H,1-2H2/t3-,4+,5+,6-,7+,9+,12+/m0/s1

InChI key:
MLSJBGYKDYSOAE-DCWMUDTNSA-N