Cardiolipin solution from bovine heart

Description

• Application: Site of action of the local anesthetic tetracaine in a phosphatidylcholine bilayer with incorporated cardiolipin.: This paper examines how tetracaine interacts with phosphatidylcholine bilayers containing cardiolipin, which has implications for understanding local anesthetic mechanisms (Shibata et al., 1995).
• Biochem/physiol Actions: Cardiolipin is a mitochondrial phospholipid that is found in mammalian tissues in low concentrations. It is often a membrane component and can inhibit cell attachment of fibronectin, vitronectin, and type I collagen.
• Physical form: Approximately 5 mg/ml in ethanol.
• Other Notes: >80% polyunsaturated fatty acid content, primarily linoleic acid.