Vincristine sulfate
meets USP testing specifications
Manufacturer: Sigma Aldrich
CAS Number: 2068-78-2
Synonym(S): Vincristine sulfate salt, 22-Oxovincaleukoblastine sulfate salt, Leurocristine sulfate salt, VCR
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 MG | V8388-1-MG | In Stock | ₹ 13,964.25 |
| 5 MG | V8388-5-MG | In Stock | ₹ 36,447.78 |
V8388 - 1 MG
In Stock
Quantity
1
Base Price: ₹ 13,964.25
GST (18%): ₹ 2,513.565
Total Price: ₹ 16,477.815
Agency
USP/NFmeets USP testing specifications
Quality Level
200
solubility
ethanol: slightly solublemethanol: solublewater: freely soluble
antibiotic activity spectrum
neoplastics
application(s)
pharmaceutical (small molecule)
Mode of action
protein synthesis | interferes
storage temp.
−20°C
SMILES string
OS(O)(=O)=O.CC[C@]1(O)CC2CN(CCc3c([nH]c4ccccc34)[C@@](C2)(C(=O)OC)c5cc6c(cc5OC)N(C=O)C7[C@](O)([C@H](OC(C)=O)[C@]8(CC)C=CCN9CC[C@]67C89)C(=O)OC)C1
InChI
1S/C46H56N4O10.H2O4S/c1-7-42(55)22-28-23-45(40(53)58-5,36-30(14-18-48(24-28)25-42)29-12-9-10-13-33(29)47-36)32-20-31-34(21-35(32)57-4)50(26-51)38-44(31)16-19-49-17-11-15-43(8-2,37(44)49)39(60-27(3)52)46(38,56)41(54)59-6;1-5(2,3)4/h9-13,15,20-21,26,28,37-39,47,55-56H,7-8,14,16-19,22-25H2,1-6H3;(H2,1,2,3,4)/t28-,37-,38+,39+,42-,43+,44+,45-,46-;/m0./s1
InChI key
AQTQHPDCURKLKT-PNYVAJAMSA-N
Other Options
Related Products
Description
- General description: Vincristine sulfate is an alkaloid present in Cantharanthus roseus.[1]
- Application: Vincristine sulfate has been used:as a positive control in potato disc anti-tumor bioassay[2]as a standard cytotoxic agent[3]to treat cells for manipulation of the microtubule network[4]
- Biochem/physiol Actions: Vincristine sulfate possesses antitumor action targeting cell cycle. It prevents the action of tubulin by inhibiting microtubule polymerization. It also causes cell death and blocks metaphase in mitosis by preventing chromosome segregation. Vincristine sulfate inhibits angiogenesis mediated by factors such as vasculature endothelial growth factor. It decreases vascularization in tumors and normal tissues.[1]
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 2 Oral - Muta. 2 - Repr. 2
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Agency: USP/NFmeets USP testing specifications
Quality Level: 200
solubility: ethanol: slightly solublemethanol: solublewater: freely soluble
antibiotic activity spectrum: neoplastics
application(s): pharmaceutical (small molecule)
Mode of action: protein synthesis | interferes
storage temp.: −20°C
SMILES string: OS(O)(=O)=O.CC[C@]1(O)CC2CN(CCc3c([nH]c4ccccc34)[C@@](C2)(C(=O)OC)c5cc6c(cc5OC)N(C=O)C7[C@](O)([C@H](OC(C)=O)[C@]8(CC)C=CCN9CC[C@]67C89)C(=O)OC)C1
InChI: 1S/C46H56N4O10.H2O4S/c1-7-42(55)22-28-23-45(40(53)58-5,36-30(14-18-48(24-28)25-42)29-12-9-10-13-33(29)47-36)32-20-31-34(21-35(32)57-4)50(26-51)38-44(31)16-19-49-17-11-15-43(8-2,37(44)49)39(60-27(3)52)46(38,56)41(54)59-6;1-5(2,3)4/h9-13,15,20-21,26,28,37-39,47,55-56H,7-8,14,16-19,22-25H2,1-6H3;(H2,1,2,3,4)/t28-,37-,38+,39+,42-,43+,44+,45-,46-;/m0./s1
InChI key: AQTQHPDCURKLKT-PNYVAJAMSA-N
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