803340
Sulfo-SDA (Sulfo-NHS-Diazirine) (sulfosuccinimidyl 4,4′-azipentanoate)
Manufacturer: Sigma Aldrich
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 MG | 803340-50-MG | In Stock | ₹ 56,820.43 |
803340 - 50 MG
In Stock
Quantity
1
Base Price: ₹ 56,820.43
GST (18%): ₹ 10,227.677
Total Price: ₹ 67,048.107
Assay
≥90%
Quality Level
100
form
powder
mol wt
327.25
reaction suitability
reagent type: cross-linking reagent
storage condition
desiccated
solubility
water: soluble
shipped in
ambient
storage temp.
2-8°C
SMILES string
O=C(C(S(=O)([O-])=O)C1)N(OC(CCC2(N=N2)C)=O)C1=O.[Na+]
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Description
- General description: Succinimidyl-diazirine (SDA) reagents are a new class of crosslinkers that combine proven amine-reactive chemistry with an innovative and efficient diazirine-based photochemistry for conjugating amine-containing molecules to nearly any other functional group. The SDA crosslinkers include six compounds differing in spacer arm lengths, ability to cleave the crosslinked proteins, and presence or absence of a charged group for membrane permeability. Protein crosslinking is an important technique used to understand protein structure and to stabilize protein-protein interactions, and these SDA reagents extend the efficiency and range of interactions that can be explored by this approach.
- Features and Benefits: Water soluble—solubility in aqueous solutions improved by a sulfonate groupHeterobifunctional—NHS ester group reacts with primary amines at pH 7 to 9 to form covalent amide bonds; diazirine (azipentanoate) group reacts efficiently with any amino acid side chain or peptide backbone upon activation with long-wave UV light (330-370 nm)Controllable—two-step chemical crosslinking is activated using common laboratory UV lampsEasy to use—these crosslinkers are photo-stable under typical laboratory lighting conditions so there is no need to perform experiments in the darkBetter than aryl azides—the diazirine photoreactive group has better photostability in normal light than phenyl azide groups of traditional photoreactive crosslinkers, yet the diazirine group is more efficiently activated by long-wave UV light
- Caution: This product is sensitive to moisture. The vial is packaged in a resealable bag with a desiccant to reduce exposure to moisture. After cold storage, equilibrate the vial to room temperature before opening to reduce condensation inside the vial. Make fresh solutions. Storage of stock solutions is not recommended. After use, return the vial to the resealable bag. Close the bag and store the product at the recommended temperature.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Assay: ≥90%
Quality Level: 100
form: powder
mol wt: 327.25
reaction suitability: reagent type: cross-linking reagent
storage condition: desiccated
solubility: water: soluble
shipped in: ambient
storage temp.: 2-8°C
SMILES string: O=C(C(S(=O)([O-])=O)C1)N(OC(CCC2(N=N2)C)=O)C1=O.[Na+]
Assay:
≥90%
Quality Level:
100
form:
powder
mol wt:
327.25
reaction suitability:
reagent type: cross-linking reagent
storage condition:
desiccated
solubility:
water: soluble
shipped in:
ambient
storage temp.:
2-8°C
SMILES string:
O=C(C(S(=O)([O-])=O)C1)N(OC(CCC2(N=N2)C)=O)C1=O.[Na+]
Assay: ≥90%
Quality Level: 100
form: powder
mol wt: 440.4
reaction suitability: reagent type: cross-linking reagent
storage condition: desiccated
solubility: water: soluble
shipped in: ambient
storage temp.: 2-8°C
SMILES string: O=C(N1OC(CCCCCNC(CCC2(N=N2)C)=O)=O)CC(S(=O)([O-])=O)C1=O.[Na+]
Assay:
≥90%
Quality Level:
100
form:
powder
mol wt:
440.4
reaction suitability:
reagent type: cross-linking reagent
storage condition:
desiccated
solubility:
water: soluble
shipped in:
ambient
storage temp.:
2-8°C
SMILES string:
O=C(N1OC(CCCCCNC(CCC2(N=N2)C)=O)=O)CC(S(=O)([O-])=O)C1=O.[Na+]
Assay: ≥95.0% (HPLC)
Quality Level: 100
form: __
mol wt: __
reaction suitability: __
storage condition: __
solubility: __
shipped in: __
storage temp.: __
SMILES string: C[C@@H]1CC[C@]2(C)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@@H](O)[C@@](C)([C@@H]5CC[C@@]34C)C(O)=O)[C@@H]2[C@H]1C
Assay:
≥95.0% (HPLC)
Quality Level:
100
form:
__
mol wt:
__
reaction suitability:
__
storage condition:
__
solubility:
__
shipped in:
__
storage temp.:
__
SMILES string:
C[C@@H]1CC[C@]2(C)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@@H](O)[C@@](C)([C@@H]5CC[C@@]34C)C(O)=O)[C@@H]2[C@H]1C
Assay: ≥90%
Quality Level: 100
form: powder
mol wt: 338.36
reaction suitability: reagent type: cross-linking reagent
storage condition: desiccated
solubility: DMSO or DMF: soluble
shipped in: ambient
storage temp.: 2-8°C
SMILES string: CC1(N=N1)CCC(NCCCCCC(ON2C(CCC2=O)=O)=O)=O
Assay:
≥90%
Quality Level:
100
form:
powder
mol wt:
338.36
reaction suitability:
reagent type: cross-linking reagent
storage condition:
desiccated
solubility:
DMSO or DMF: soluble
shipped in:
ambient
storage temp.:
2-8°C
SMILES string:
CC1(N=N1)CCC(NCCCCCC(ON2C(CCC2=O)=O)=O)=O