901487
(S,S,S)-AHPC hydrochloride
≥97%
Manufacturer: Sigma Aldrich
CAS Number: 2115897-23-7
Synonym(S): (2S,4S)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride, E3 Ligase ligand negative control epimer, Ligand for PROTAC® research, VH032 negative control
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 MG | 901487-10-MG | In Stock | ₹ 20,037.08 |
| 100 MG | 901487-100-MG | In Stock | ₹ 56,590.00 |
901487 - 10 MG
In Stock
Quantity
1
Base Price: ₹ 20,037.08
GST (18%): ₹ 3,606.674
Total Price: ₹ 23,643.754
ligand
VH032
Quality Level
100
Assay
≥97%
form
powder or crystals
reaction suitability
reagent type: ligand
storage temp.
2-8°C
SMILES string
N[C@H](C(N1[C@H](C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@H](O)C1)=O)C(C)(C)C.Cl
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Medchemexpress LLC HY-125845A 100mg , (S,S,S)-AHPC (hydrochloride) CAS:2115897-23-7 Purity:>98% | Medchemexpress LLC | ₹ 28,748.16 | |
 | Sigma Aldrich Fine Chemicals Biosciences (S,S,S)-AHPC hydrochloride >=97% | 2115897-23-7 | 10MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 31,443.30 | |
 | (S,S,S)-AHPC (hydrochloride) | ChemScene | ₹ 12,491.76 - ₹ 1,33,815.84 | |
 | 2115897-23-7 | (2S,4S)-1-[(2S)-2-Amino-3,3-dimethyl-butanoyl]-4-hydroxy-N-[[4-(4-methylthiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide hydrochloride | A2B Chem | ₹ 11,037.24 - ₹ 1,32,703.56 |
Related Products
Description
- Application: (S,S,S)-AHPC (HCl salt) is a ligand used as a negative control for (S,R,S)-AHPC (cat# 901490) in the recruitment of the von Hippel–Lindau (VHL) protein for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology.
- Other Notes: Technology Spotlight: Degrader Building Blocks for Targeted Protein DegradationPortal: Building PROTAC® Degraders for Targeted Protein DegradationSelective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4Small-Molecule PROTACS: New Approaches to Protein DegradationIdentification and Characterization of Von Hippel-Lindau-Recruiting Proteolysis Targeting Chimeras (PROTACs) of TANK-Binding Kinase 1Group-Based Optimization of Potent and Cell-Active Inhibitors of the von Hippel–Lindau (VHL) E3 Ubiquitin Ligase: Structure–Activity Relationships Leading to the Chemical Probe (2S,4R)-1-((S)-2-(1-Cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (VH298)
- Legal Information: PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
ligand: VH032
Quality Level: 100
Assay: ≥97%
form: powder or crystals
reaction suitability: reagent type: ligand
storage temp.: 2-8°C
SMILES string: N[C@H](C(N1[C@H](C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@H](O)C1)=O)C(C)(C)C.Cl
ligand:
VH032
Quality Level:
100
Assay:
≥97%
form:
powder or crystals
reaction suitability:
reagent type: ligand
storage temp.:
2-8°C
SMILES string:
N[C@H](C(N1[C@H](C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@H](O)C1)=O)C(C)(C)C.Cl
ligand: VH032
Quality Level: 100
Assay: ≥95%
form: powder or crystals
reaction suitability: reactivity: carboxyl reactivereagent type: ligand-linker conjugate
storage temp.: 2-8°C
SMILES string: O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H](C[C@@H](O)C3)N3C([C@H](C(C)(C)C)NC(COCCOCCN)=O)=O.Cl
ligand:
VH032
Quality Level:
100
Assay:
≥95%
form:
powder or crystals
reaction suitability:
reactivity: carboxyl reactivereagent type: ligand-linker conjugate
storage temp.:
2-8°C
SMILES string:
O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H](C[C@@H](O)C3)N3C([C@H](C(C)(C)C)NC(COCCOCCN)=O)=O.Cl
ligand: VH032
Quality Level: 100
Assay: ≥97%
form: powder or crystals
reaction suitability: reagent type: ligand
storage temp.: 2-8°C
SMILES string: N[C@H](C(N1[C@H](C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O)C(C)(C)C.Cl
ligand:
VH032
Quality Level:
100
Assay:
≥97%
form:
powder or crystals
reaction suitability:
reagent type: ligand
storage temp.:
2-8°C
SMILES string:
N[C@H](C(N1[C@H](C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O)C(C)(C)C.Cl
ligand: VH032
Quality Level: 100
Assay: ≥95%
form: powder or crystals
reaction suitability: reactivity: carboxyl reactivereagent type: ligand-linker conjugate
storage temp.: 2-8°C
SMILES string: O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H](C[C@@H](O)C3)N3C([C@H](C(C)(C)C)NC(COCCN)=O)=O.Cl
ligand:
VH032
Quality Level:
100
Assay:
≥95%
form:
powder or crystals
reaction suitability:
reactivity: carboxyl reactivereagent type: ligand-linker conjugate
storage temp.:
2-8°C
SMILES string:
O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H](C[C@@H](O)C3)N3C([C@H](C(C)(C)C)NC(COCCN)=O)=O.Cl