VH032-cyclopropane-F
≥95%
Manufacturer: Sigma Aldrich
CAS Number: 2306193-99-5
Synonym(S): (S,R,S)-AHPC-cyclopropane-F, (2S,4R)-1-((S)-2-(1-Fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide, (2S,4R)-1-[(S)-2-(1-Fluorocyclopropan-1-ylcarbonylamino)-3,3-dimethylbutanoyl]-4-hydroxy-N-[2-hydroxy-4-(4-methylthiazol-5-yl)benzyl]pyrrolidine-2-carboxamide, N-[(1-fluorocyclopropyl)carbonyl]-3-methyl-L-valyl-4-hydroxy-N-[[2-hydroxy-4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-, L-Prolinamide
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 MG | 930601-50-MG | In Stock | ₹ 20,490.00 |
930601 - 50 MG
In Stock
Quantity
1
Base Price: ₹ 20,490.00
GST (18%): ₹ 3,688.20
Total Price: ₹ 24,178.20
ligand
VH032
Quality Level
100
Assay
≥95%
form
powder
reaction suitability
reagent type: ligand
functional group
hydroxyl
storage temp.
2-8°C
SMILES string
C([C@@H](NC(=O)C1(F)CC1)[C@@](C)(C)C)(=O)N2[C@H](C(NCC3=C(O)C=C(C=C3)C4=C(C)N=CS4)=O)C[C@@H](O)C2
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris™ VH 101, phenol | Tocris™ | ₹ 76,105.62 | |
 | Medchemexpress LLC HY-125905 250mg , VH032-cyclopropane-F CAS:2306193-99-5 Purity:>98% | Medchemexpress LLC | ₹ 57,496.32 | |
 | eMolecules Ambeed / (2S4R)-1-((S)-2-(1-Fluorocyclopropanecarboxamido)-33-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide / 25mg / 768956994 / A1220565 / / 2306193-99-5 / [null] / 532.630 / C26H33FN4O5S | eMolecules | ₹ 14,105.42 | |
 | VH032-cyclopropane-F | ChemScene | ₹ 9,839.40 - ₹ 1,54,435.80 |
Related Products
Description
- Application: VH032-cyclopropane-F is a functionalized von-Hippel-Lindau (VHL) ligand with a terminal hydroxyl group. Allows rapid conjugation with many linkers containing active leaving groups. A basic building block for development of a protein degrader library.Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation Protein Degrader Building Blocks
- Other Notes: Targeted Protein Degradation by Small MoleculesDestruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O′PROTAC): Effective Targeting of LEF1 and ERG3Small-Molecule PROTACS: New Approaches to Protein DegradationTargeted Protein Degradation: from Chemical Biology to Drug DiscoveryImpact of linker length on the activity of PROTACs
- Legal Information: PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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ligand: VH032
Quality Level: 100
Assay: ≥95%
form: powder
reaction suitability: reagent type: ligand
functional group: hydroxyl
storage temp.: 2-8°C
SMILES string: C([C@@H](NC(=O)C1(F)CC1)[C@@](C)(C)C)(=O)N2[C@H](C(NCC3=C(O)C=C(C=C3)C4=C(C)N=CS4)=O)C[C@@H](O)C2
ligand: VH032
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Assay: ≥95%
form: powder
reaction suitability: __
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SMILES string: __
ligand: pomalidomide
Quality Level: 100
Assay: ≥95%
form: powder
reaction suitability: __
functional group: amine
storage temp.: 2-8°C
SMILES string: O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCN)=CC=C3)=O)=O.Cl
