916978
BocA1V2PF1
≥95%
Manufacturer: Sigma Aldrich
Synonym(S): ((S)-2-((S)-2-((tert-Butoxycarbonyl)amino)propanamido)-2-cyclohexylacetyl)-L-prolyl-L-phenylalanine, AVP ligand, IAP E3 ligase lead for protein degrader research, SNIPER building block
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 MG | 916978-100-MG | In Stock | ₹ 48,896.53 |
916978 - 100 MG
In Stock
Quantity
1
Base Price: ₹ 48,896.53
GST (18%): ₹ 8,801.375
Total Price: ₹ 57,697.905
ligand
BocA1V2PF1
Quality Level
100
Assay
≥95%
form
powder
reaction suitability
reagent type: ligand
functional group
carboxylic acid
storage temp.
2-8°C
SMILES string
C[C@H](NC(OC(C)(C)C)=O)C(N[C@H](C(N1CCC[C@H]1C(N[C@H](C(O)=O)CC2=CC=CC=C2)=O)=O)C3CCCCC3)=O
Related Products
Description
- Application: BocA1V2PF1 is an in silico-derived inhibitor of apoptosis protein (IAP)-recruiting ligand for targeted protein degradation and SNIPER (specific and non-genetic IAP-dependent protein erasers) development, launched in partnership with ComInnex. Learn more about the novel IAP ligands generated through virtual screening of AVP mimetics in our Technology Spotlight. A C-terminal variant of BocA1V2PF1 is also available as A1V2PF1-NHEt (917222).BocA1V2PF1 conjugates are also available for degrader synthesis. Browse our full synthesis offering here for streamlining SNIPER and PROTAC® degrader libraries: Degrader Building Blocks917966 BocA1V2PF1-NHC6-NH2916706 BocA1V2PF1-NHC10-NH2916951 BocA1V2PF1-NHPEG1-NH2917214 BocA1V2PF1-NHPEG3-NH2Technology Spotlight: Degrader Building Blocks with Inhibitor of Apoptosis Protein (IAP) In Silico-Derived Ligands
- Other Notes: In Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs)SNIPERs−Hijacking IAP activity to induce protein degradationE3 Ligase Ligands for PROTACs: How They Were Found and How to Discover New Ones
- Legal Information: PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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ligand: BocA1V2PF1
Quality Level: 100
Assay: ≥95%
form: powder
reaction suitability: reagent type: ligand
functional group: carboxylic acid
storage temp.: 2-8°C
SMILES string: C[C@H](NC(OC(C)(C)C)=O)C(N[C@H](C(N1CCC[C@H]1C(N[C@H](C(O)=O)CC2=CC=CC=C2)=O)=O)C3CCCCC3)=O
ligand:
BocA1V2PF1
Quality Level:
100
Assay:
≥95%
form:
powder
reaction suitability:
reagent type: ligand
functional group:
carboxylic acid
storage temp.:
2-8°C
SMILES string:
C[C@H](NC(OC(C)(C)C)=O)C(N[C@H](C(N1CCC[C@H]1C(N[C@H](C(O)=O)CC2=CC=CC=C2)=O)=O)C3CCCCC3)=O
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Quality Level: 100
Assay: __
form: powder
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form: liquid
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ligand:
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Quality Level:
100
Assay:
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form:
liquid
reaction suitability:
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functional group:
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storage temp.:
2-8°C
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