911690

C5 Lenalidomide

≥95%

Manufacturer: Sigma Aldrich

CAS Number: 191732-70-4

Synonym(S): 3-(5-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione, E3 ligase ligand, Ligand for PROTAC® research

Select a Size

Pack Size SKU Availability Price
100 MG 911690-100-MG In Stock ₹ 31,522.40

911690 - 100 MG

₹ 31,522.40

In Stock

Quantity

1

Base Price: ₹ 31,522.40

GST (18%): ₹ 5,674.032

Total Price: ₹ 37,196.432

ligand

C5 Lenalidomide

Quality Level

100

Assay

≥95%

form

powder

reaction suitability

reagent type: ligand

storage temp.

2-8°C

SMILES string

NC1=CC=C2C(CN(C3CCC(NC3=O)=O)C2=O)=C1

Other Options

Image Product Name Manufacturer Price Range
76-775-0
Tocris Bioscience™ Lenalidomide 5'-amine
Tocris Bioscience™ ₹ 32,512.80
CS-0181936
C5 Lenalidomide
ChemScene ₹ 4,363.56 - ₹ 1,35,954.84
BF51470
191732-70-4 | 3-(5-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione
A2B Chem ₹ 7,358.16 - ₹ 1,49,558.88

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Description

  • Application: C5 Lenalidomide is a derivative of the Cereblon (CRBN)-binding ligand lenalidomide, which possesses an amine at the C4 position. C5 Lenalidomide can be used to bind the CRBN E3 ubiquitin ligase in targeted protein degradation research or in the synthesis of protein degraders with a C5 exit vector. Learn more about proteolysis-targeting chimeras (PROTACs) and the building blocks to design them in our Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation
  • Other Notes: Technology Spotlight: Degrader Building Blocks for Targeted Protein DegradationPortal: Building PROTAC® Degraders for Targeted Protein DegradationAmino-substituted thalidomide analogs: potent inhibitors of TNF-alpha productionTargeted Protein Degradation by Small Molecules
  • Legal Information: PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

SAFETY INFORMATION

Pictograms

GHS08

Signal Word

Warning

Hazard Statements

H361d,H373

Precautionary Statements

P202 - P260 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 2 - STOT RE 2

Target Organs

Blood

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Sigma Aldrich

911690

≥95%...


ligand:
C5 Lenalidomide

Quality Level:
100

Assay:
≥95%

form:
powder

reaction suitability:
reagent type: ligand

storage temp.:
2-8°C

SMILES string:
NC1=CC=C2C(CN(C3CCC(NC3=O)=O)C2=O)=C1

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100

Assay:
≥95%

form:
powder or crystals

reaction suitability:
reactivity: carboxyl reactivereagent type: ligand-linker conjugate

storage temp.:
2-8°C

SMILES string:
O=C1N(C2CCC(NC2=O)=O)CC3=CC(NC(CCCN)=O)=CC=C31.Cl

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Sigma Aldrich

911712

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ligand:
C5 Lenalidomide

Quality Level:
100

Assay:
≥95%

form:
powder or crystals

reaction suitability:
reactivity: carboxyl reactivereagent type: ligand-linker conjugate

storage temp.:
2-8°C

SMILES string:
O=C1N(C2CCC(NC2=O)=O)CC3=CC(NC(CCCCCCN)=O)=CC=C31.Cl

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Sigma Aldrich

911720

≥95%...


ligand:
C5 Lenalidomide

Quality Level:
100

Assay:
≥95%

form:
powder

reaction suitability:
reactivity: carboxyl reactivereagent type: ligand-linker conjugate

storage temp.:
2-8°C

SMILES string:
O=C1N(C2CCC(NC2=O)=O)CC3=CC(NC(CCCCCCCCCN)=O)=CC=C31.Cl