930652
Pomalidomide-C2-NH2 hydrochloride
≥95%
Manufacturer: Sigma Aldrich
CAS Number: 2305369-00-8
Synonym(S): 4-((2-aminoethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride, 4-[(2-Aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione, E3 Ligase Ligand 17
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 MG | 930652-100-MG | In Stock | ₹ 7,740.00 |
| 500 MG | 930652-500-MG | In Stock | ₹ 29,590.00 |
930652 - 100 MG
In Stock
Quantity
1
Base Price: ₹ 7,740.00
GST (18%): ₹ 1,393.20
Total Price: ₹ 9,133.20
ligand
pomalidomide
Quality Level
100
Assay
≥95%
form
powder
functional group
amine
storage temp.
2-8°C
SMILES string
O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCN)=CC=C3)=O)=O.Cl
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Medchemexpress LLC HY-128846A 5mg Medchemexpress, Pomalidomide-C2-NH2 (hydrochloride) CAS:2305369-00-8 Purity:>98% | Medchemexpress LLC | ₹ 5,839.47 | |
 | Pomalidomide-C2-NH2 hydrochloride | ChemScene | ₹ 7,700.40 - ₹ 87,955.68 |
Related Products
Description
- Application: Pomalidomide-C2-NH2 Hydrochloride is a functionalized cereblon ligand for development of pomalidomide-based PROTACs. Allows rapid conjugation with carboxyl linkers due to the presence of an amine group via peptide coupling reactions. It is also active for linker attachment via reductive amination, and a basic building block for development of a protein degrader library.Technology Spotlight: Degrader Building Blocks for Targeted Protein DegradationProtein Degrader Building Blocks
- Other Notes: Targeted Protein Degradation by Small MoleculesDestruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O′PROTAC): Effective Targeting of LEF1 and ERGSmall-Molecule PROTACS: New Approaches to Protein DegradationTargeted Protein Degradation: from Chemical Biology to Drug DiscoveryImpact of linker length on the activity of PROTACs
- Legal Information: PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
ligand: pomalidomide
Quality Level: 100
Assay: ≥95%
form: powder
functional group: amine
storage temp.: 2-8°C
SMILES string: O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCN)=CC=C3)=O)=O.Cl
ligand:
pomalidomide
Quality Level:
100
Assay:
≥95%
form:
powder
functional group:
amine
storage temp.:
2-8°C
SMILES string:
O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCN)=CC=C3)=O)=O.Cl
ligand: pomalidomide
Quality Level: 100
Assay: ≥95%
form: powder
functional group: amine
storage temp.: 2-8°C
SMILES string: O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCOCCOCCOCCN)=CC=C3)=O)=O
ligand:
pomalidomide
Quality Level:
100
Assay:
≥95%
form:
powder
functional group:
amine
storage temp.:
2-8°C
SMILES string:
O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCOCCOCCOCCN)=CC=C3)=O)=O
ligand: __
Quality Level: 100
Assay: ≥95%
form: powder
functional group: amine
storage temp.: 2-8°C
SMILES string: NCC1=C(C(N(C2CCC(NC2=O)=O)C3=O)=O)C3=CC=C1
ligand:
__
Quality Level:
100
Assay:
≥95%
form:
powder
functional group:
amine
storage temp.:
2-8°C
SMILES string:
NCC1=C(C(N(C2CCC(NC2=O)=O)C3=O)=O)C3=CC=C1
ligand: pomalidomide
Quality Level: 100
Assay: ≥95.0%
form: powder
functional group: carboxylic acid
storage temp.: 2-8°C
SMILES string: __
ligand:
pomalidomide
Quality Level:
100
Assay:
≥95.0%
form:
powder
functional group:
carboxylic acid
storage temp.:
2-8°C
SMILES string:
__