930660
Pomalidomide 4′-PEG3-amine hydrochloride
≥95%
Manufacturer: Sigma Aldrich
CAS Number: 2446474-09-3
Synonym(S): 1H-Isoindole-1,3(2H)-dione hydrochloride, 4-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethylamino]-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione hydrochloride, 4-[[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidinyl) hydrochloride
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 MG | 930660-50-MG | In Stock | ₹ 23,220.00 |
930660 - 50 MG
In Stock
Quantity
1
Base Price: ₹ 23,220.00
GST (18%): ₹ 4,179.60
Total Price: ₹ 27,399.60
ligand
pomalidomide
Quality Level
100
Assay
≥95%
form
powder
functional group
amine
storage temp.
2-8°C
SMILES string
O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCOCCOCCOCCN)=CC=C3)=O)=O
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | 2446474-09-3 | Pomalidomide 4'-PEG3-amine | A2B Chem | ₹ 8,384.88 - ₹ 92,233.68 |
Related Products
Description
- Application: Pomalidomide 4′-PEG3-amine Hydrochloride is a functionalized cereblon ligand for development of pomalidomide-based PROTACs. Allows rapid conjugation with carboxyl linkers due to the presence of an amine group via peptide coupling reactions. It is also active for linker attachment via reductive amination, and a basic building block for development of a protein degrader library.Technology Spotlight: Degrader Building Blocks for Targeted Protein DegradationProtein Degrader Building BlocksAutomate your CRBN-PEG based PROTACs with Synple Automated Synthesis Platform (SYNPLE-SC002)
- Other Notes: Targeted Protein Degradation by Small Molecules Destruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O′PROTAC): Effective Targeting of LEF1 and ERG Small-Molecule PROTACS: New Approaches to Protein DegradationTargeted Protein Degradation: from Chemical Biology to Drug Discovery Impact of linker length on the activity of PROTACs
- Legal Information: PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
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ligand: pomalidomide
Quality Level: 100
Assay: ≥95%
form: powder
functional group: amine
storage temp.: 2-8°C
SMILES string: O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCOCCOCCOCCN)=CC=C3)=O)=O
ligand:
pomalidomide
Quality Level:
100
Assay:
≥95%
form:
powder
functional group:
amine
storage temp.:
2-8°C
SMILES string:
O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCOCCOCCOCCN)=CC=C3)=O)=O
ligand: __
Quality Level: 100
Assay: ≥95%
form: powder
functional group: amine
storage temp.: 2-8°C
SMILES string: NCC1=C(C(N(C2CCC(NC2=O)=O)C3=O)=O)C3=CC=C1
ligand:
__
Quality Level:
100
Assay:
≥95%
form:
powder
functional group:
amine
storage temp.:
2-8°C
SMILES string:
NCC1=C(C(N(C2CCC(NC2=O)=O)C3=O)=O)C3=CC=C1
ligand: pomalidomide
Quality Level: 100
Assay: ≥95.0%
form: powder
functional group: carboxylic acid
storage temp.: 2-8°C
SMILES string: __
ligand:
pomalidomide
Quality Level:
100
Assay:
≥95.0%
form:
powder
functional group:
carboxylic acid
storage temp.:
2-8°C
SMILES string:
__
ligand: __
Quality Level: 100
Assay: ≥95%
form: powder
functional group: amine
storage temp.: 2-8°C
SMILES string: O=C1NC(C(CC1)N2C(C3=CC=C(C=C3C2=O)OC4CCNCC4)=O)=O
ligand:
__
Quality Level:
100
Assay:
≥95%
form:
powder
functional group:
amine
storage temp.:
2-8°C
SMILES string:
O=C1NC(C(CC1)N2C(C3=CC=C(C=C3C2=O)OC4CCNCC4)=O)=O