930717

1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-(4-piperidinyloxy) hydrochloride

≥95%

Manufacturer: Sigma Aldrich

CAS Number: 2640388-58-3

Select a Size

Pack Size SKU Availability Price
50 MG 930717-50-MG In Stock ₹ 24,130.00

930717 - 50 MG

₹ 24,130.00

In Stock

Quantity

1

Base Price: ₹ 24,130.00

GST (18%): ₹ 4,343.40

Total Price: ₹ 28,473.40

Quality Level

100

Assay

≥95%

form

powder

functional group

amine

storage temp.

2-8°C

SMILES string

O=C1NC(C(CC1)N2C(C3=CC=C(C=C3C2=O)OC4CCNCC4)=O)=O

Other Options

Image Product Name Manufacturer Price Range
CS-1049935
2-(2,6-Dioxopiperidin-3-yl)-5-(piperidin-4-yloxy)isoindoline-1,3-dione hydrochloride
ChemScene --
BL22263
2640388-58-3 |
A2B Chem --

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Description

  • Application: 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-(4-piperidinyloxy) Hydrochloride is a functionalized Cereblon ligand used for development of protein degrader building blocks. Contains a terminal amine group, allowing rapid conjugation of carboxyl containing linkers. A basic building block for development of a protein degrader library.Technology Spotlight: Degrader Building Blocks for Targeted Protein DegradationProtein Degrader Building Blocks
  • Other Notes: Targeted Protein Degradation by Small MoleculesDestruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O′PROTAC): Effective Targeting of LEF1 and ERGSmall-Molecule PROTACS: New Approaches to Protein DegradationTargeted Protein Degradation: from Chemical Biology to Drug DiscoveryImpact of linker length on the activity of PROTACs
  • Legal Information: PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

SAFETY INFORMATION

Pictograms

GHS08

Signal Word

Danger

Hazard Statements

H360D

Precautionary Statements

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 1B

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Sigma Aldrich

930717

≥95%...


Quality Level:
100

Assay:
≥95%

form:
powder

functional group:
amine

storage temp.:
2-8°C

SMILES string:
O=C1NC(C(CC1)N2C(C3=CC=C(C=C3C2=O)OC4CCNCC4)=O)=O

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O=C1NC(=O)C(N2C(=O)C=3C=CC=C(C#CCCO)C3C2)CC1

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100

Assay:
≥95.0%

form:
powder

functional group:
carboxylic acid

storage temp.:
2-8°C

SMILES string:
O=C(O)CCCCCC#CC1=CC=CC=2C(=O)N(CC12)C3C(=O)NC(=O)CC3

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Supelco

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analytical standard...


Quality Level:
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Assay:
__

form:
__

functional group:
__

storage temp.:
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SMILES string:
OS(O)(=O)=O.Nc1ccc(N)c(Cl)c1