911798
N-(4-Bromophenyl)-N-phenylacrylamide
≥95%
Manufacturer: Sigma Aldrich
CAS Number: 1956368-15-2
Synonym(S): Electrophilic scout fragment, KB05, Scout fragment for targetable cysteine
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 MG | 911798-100-MG | In Stock | ₹ 22,830.00 |
911798 - 100 MG
In Stock
Quantity
1
Base Price: ₹ 22,830.00
GST (18%): ₹ 4,109.40
Total Price: ₹ 26,939.40
Quality Level
100
Assay
≥95%
form
(Powder or crystals or solid or chunks)
storage temp.
2-8°C
Related Products
Description
- Application: N-(4-Bromophenyl)-N-phenylacrylamide is a cysteine-reactive small-molecule fragment for chemoproteomic and ligandability studies for both traditionally druggable proteins as well as ″undruggable,″ or difficult-to-target, proteins. This fragment electrophile, or ″scout″ fragment, can be used alone in fragment-based covalent ligand discovery or incorporated into bifunctional tools such as electrophilic PROTAC® molecules for targeted protein degradation as demonstrated by the Cravatt Lab for E3 ligase discovery.
- Other Notes: Technology Spotlight: Proteomic Ligandability AssessmentProteome-wide covalent ligand discovery in native biological systemsElectrophilic PROTACs that degrade nuclear proteins by engaging DCAF16
- Legal Information: PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
SAFETY INFORMATION
WGK
WGK 3
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