912131
2-Chloro-1-(6-methoxy-1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-one
≥95%
Manufacturer: Sigma Aldrich
CAS Number: 57368-84-0
Synonym(S): 1-(Chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl methyl ether, 2-Chloro-1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)ethan-1-one, Electrophilic scout fragment, KB02, Scout fragment for targetable cysteine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 MG | 912131-100-MG | In Stock | ₹ 15,274.08 |
912131 - 100 MG
In Stock
Quantity
1
Base Price: ₹ 15,274.08
GST (18%): ₹ 2,749.334
Total Price: ₹ 18,023.414
Quality Level
100
Assay
≥95%
form
chunks
storage temp.
2-8°C
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | 2-Chloro-1-(6-methoxy-1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-one | ChemScene | ₹ 5,607.00 - ₹ 73,781.00 | |
 | 57368-84-0 | 2-Chloro-1-(6-methoxy-1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-one | A2B Chem | ₹ 8,277.00 - ₹ 31,506.00 |
Related Products
Description
- Application: 2-Chloro-1-(6-methoxy-1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-one is a cysteine-reactive small-molecule fragment for chemoproteomic and ligandability studies for both traditionally druggable proteins as well as "undruggable," or difficult-to-target, proteins. This fragment electrophile, or "scout" fragment, can be used alone in fragment-based covalent ligand discovery or incorporated into bifunctional tools such as electrophilic PROTAC® molecules for targeted protein degradation as demonstrated by the Cravatt Lab Lab for E3 ligase discovery.
- Other Notes: Technology Spotlight: Proteomic Ligandability AssessmentThe Proteome-Wide Potential for Reversible Covalency at CysteineElectrophilic PROTACs that degrade nuclear proteins by engaging DCAF16Proteome-wide covalent ligand discovery in native biological systems
- Legal Information: PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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