930709

Pomalidomide-piperazine-propanoic acid

≥95.0%

Manufacturer: Sigma Aldrich

CAS Number: 2591176-24-6

Synonym(S): 1-Piperazinepropanoic acid, 3-(4-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)piperazin-1-yl)propanoic acid, 4-[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]

Select a Size

Pack Size SKU Availability Price
50 MG 930709-50-MG In Stock ₹ 16,850.00

930709 - 50 MG

₹ 16,850.00

In Stock

Quantity

1

Base Price: ₹ 16,850.00

GST (18%): ₹ 3,033.00

Total Price: ₹ 19,883.00

ligand

pomalidomide

Quality Level

100

Assay

≥95.0%

form

powder

functional group

carboxylic acid

storage temp.

2-8°C

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Description

  • Application: Pomalidomide-piperazine-propanoic acid is a functionalized Cereblon ligand used for development of pomalidomide-based degrader building blocks. Contains a terminal carboxyl group, allowing rapid conjugation of amine containing linkers. A basic building block for development of a protein degrader library. Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation Protein Degrader Building Blocks
  • Other Notes: Targeted Protein Degradation by Small MoleculesDestruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O′PROTAC): Effective Targeting of LEF1 and ERGSmall-Molecule PROTACS: New Approaches to Protein DegradationTargeted Protein Degradation: from Chemical Biology to Drug DiscoveryImpact of linker length on the activity of PROTACs
  • Legal Information: PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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