930571
Pomalidomide-piperidine-carboxylic acid
≥95%
Manufacturer: Sigma Aldrich
CAS Number: 2467965-70-2
Synonym(S): 1-[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl], 1-[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-isoindolin-5-yl]piperidine-4-carboxylic acid, 4-Piperidinecarboxylic acid
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 MG | 930571-50-MG | In Stock | ₹ 14,776.13 |
930571 - 50 MG
In Stock
Quantity
1
Base Price: ₹ 14,776.13
GST (18%): ₹ 2,659.703
Total Price: ₹ 17,435.833
ligand
pomalidomide
Quality Level
100
Assay
≥95%
form
powder
functional group
carboxylic acid
storage temp.
2-8°C
SMILES string
O=C(O)C1CCN(C2=CC=C3C(=O)N(C(=O)C3=C2)C4C(=O)NC(=O)CC4)CC1
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | 1-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)piperidine-4-carboxylic acid | ChemScene | ₹ 29,004.84 |
Related Products
Description
- Application: Pomalidomide-piperidine-carboxylic acid is a functionalized cereblon ligand for development of pomalidomide-based PROTACs. Allows rapid conjugation with amine linkers due to the presence of a carboxyl group via peptide coupling reactions. A basic building block for development of a protein degrader library.Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation Protein Degrader Building Blocks
- Other Notes: Targeted Protein Degradation by Small Molecules Destruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O′PROTAC): Effective Targeting of LEF1 and ERG Small-Molecule PROTACS: New Approaches to Protein Degradation Targeted Protein Degradation: from Chemical Biology to Drug Discovery Impact of linker length on the activity of PROTACs
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Repr. 1B
WGK
WGK 3
Compare Similar Items
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ligand: pomalidomide
Quality Level: 100
Assay: ≥95%
form: powder
functional group: carboxylic acid
storage temp.: 2-8°C
SMILES string: O=C(O)C1CCN(C2=CC=C3C(=O)N(C(=O)C3=C2)C4C(=O)NC(=O)CC4)CC1
ligand:
pomalidomide
Quality Level:
100
Assay:
≥95%
form:
powder
functional group:
carboxylic acid
storage temp.:
2-8°C
SMILES string:
O=C(O)C1CCN(C2=CC=C3C(=O)N(C(=O)C3=C2)C4C(=O)NC(=O)CC4)CC1
ligand: VH032
Quality Level: 100
Assay: ≥95%
form: powder
functional group: hydroxyl
storage temp.: 2-8°C
SMILES string: __
ligand:
VH032
Quality Level:
100
Assay:
≥95%
form:
powder
functional group:
hydroxyl
storage temp.:
2-8°C
SMILES string:
__
ligand: VH032
Quality Level: 100
Assay: ≥95%
form: powder
functional group: hydroxyl
storage temp.: 2-8°C
SMILES string: C([C@@H](NC(=O)C1(F)CC1)[C@@](C)(C)C)(=O)N2[C@H](C(NCC3=C(O)C=C(C=C3)C4=C(C)N=CS4)=O)C[C@@H](O)C2
ligand:
VH032
Quality Level:
100
Assay:
≥95%
form:
powder
functional group:
hydroxyl
storage temp.:
2-8°C
SMILES string:
C([C@@H](NC(=O)C1(F)CC1)[C@@](C)(C)C)(=O)N2[C@H](C(NCC3=C(O)C=C(C=C3)C4=C(C)N=CS4)=O)C[C@@H](O)C2
ligand: VH032
Quality Level: 100
Assay: ≥95%
form: powder
functional group: carboxylic acid
storage temp.: 2-8°C
SMILES string: __
ligand:
VH032
Quality Level:
100
Assay:
≥95%
form:
powder
functional group:
carboxylic acid
storage temp.:
2-8°C
SMILES string:
__