930539
(S,R,S)-AHPC-Me-C5-COOH
≥95%
Manufacturer: Sigma Aldrich
CAS Number: 2229976-21-8
Synonym(S): 6-{[(2S)-1-[(2S,4R)-4-Hydroxy-2-{[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]carbamoyl}pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamoyl}hexanoic acid, 7-(((S)-1-((2S, 4R)-4-Hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-7-oxoheptanoic acid, L-Prolinamide, N-(6-carboxy-1-oxohexyl)-3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 MG | 930539-50-MG | In Stock | ₹ 22,180.43 |
930539 - 50 MG
In Stock
Quantity
1
Base Price: ₹ 22,180.43
GST (18%): ₹ 3,992.477
Total Price: ₹ 26,172.907
ligand
VH032
Quality Level
100
Assay
≥95%
form
powder
functional group
carboxylic acid
storage temp.
2-8°C
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | (S,R,S)-AHPC-Me-C5-COOH | Aaron Chemicals LLC | ₹ 20,791.08 - ₹ 1,33,388.04 | |
 | (S,R,S)-AHPC-Me-C5-COOH | ChemScene | ₹ 18,823.20 - ₹ 29,946.00 |
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Description
- Application: (S,R,S)-AHPC-Me-C5-COOH is a functionalized von-Hippel-Lindau (VHL) ligand with a terminal carboxyl group, allowing rapid conjugation of amine containing linkers. A basic building block for development of a protein degrader library. Technology Spotlight: Degrader Building Blocks for Targeted Protein DegradationProtein Degrader Building Blocks
- Other Notes: Targeted Protein Degradation by Small MoleculesDestruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O′PROTAC): Effective Targeting of LEF1 and ERGSmall-Molecule PROTACS: New Approaches to Protein DegradationTargeted Protein Degradation: from Chemical Biology to Drug Discovery Impact of linker length on the activity of PROTACs
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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