923818
N-(But-3-yn-1-yl)-2-(((2-oxo-2H-chromen-7-yl)oxy)methyl)acrylamide
Manufacturer: Sigma Aldrich
Synonym(S): Coumarin alkyne CoLDR probe
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 MG | 923818-50-MG | In Stock | ₹ 26,040.00 |
| 100 MG | 923818-100-MG | In Stock | ₹ 35,950.00 |
923818 - 50 MG
In Stock
Quantity
1
Base Price: ₹ 26,040.00
GST (18%): ₹ 4,687.20
Total Price: ₹ 30,727.20
reaction suitability
reagent type: chemical modification reagentreaction type: click chemistry
Quality Level
100
functional group
(Alkyne)
storage temp.
2-8°C
SMILES string
O=C1OC2=CC(OCC(C(NCCC#C)=O)=C)=CC=C2C=C1
Related Products
Description
- Application: N-(But-3-yn-1-yl)-2-(((2-oxo-2H-chromen-7-yl)oxy)methyl)acrylamide is a proteomic cysteine probe. As described in Reddi et al, the Nir London lab developed a-substituted N-alkynyl-methacrylamides for covalent ligand directed release chemistry (CoLDR). CoLDR represents a new type of acrylamide-based electrophiles for targeted covalent inhibitor discovery and design. Specifically this CoLDR probe is a coumarin derivative with a terminal alkyne for click chemistry.
- Other Notes: Chemical Biology ToolsClick Chemistry Reagents
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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reaction suitability: reagent type: chemical modification reagentreaction type: click chemistry
Quality Level: 100
functional group: (Alkyne)
storage temp.: 2-8°C
SMILES string: O=C1OC2=CC(OCC(C(NCCC#C)=O)=C)=CC=C2C=C1
reaction suitability:
reagent type: chemical modification reagentreaction type: click chemistry
Quality Level:
100
functional group:
(Alkyne)
storage temp.:
2-8°C
SMILES string:
O=C1OC2=CC(OCC(C(NCCC#C)=O)=C)=CC=C2C=C1
reaction suitability: __
Quality Level: 100
functional group: __
storage temp.: 2-8°C
SMILES string: CO[C@H]1[C@@H](O)[C@H](O)[C@H](O/C(C=O)=C\C([O-])=O)O[C@@H]1C([O-])=O.OC2[C@H](OC(O)C=O)[C@@H](C([O-])=O)O[C@@H](OC)[C@H]2O
reaction suitability:
__
Quality Level:
100
functional group:
__
storage temp.:
2-8°C
SMILES string:
CO[C@H]1[C@@H](O)[C@H](O)[C@H](O/C(C=O)=C\C([O-])=O)O[C@@H]1C([O-])=O.OC2[C@H](OC(O)C=O)[C@@H](C([O-])=O)O[C@@H](OC)[C@H]2O
reaction suitability: __
Quality Level: 100
functional group: __
storage temp.: 2-8°C
SMILES string: CO[C@H]1[C@@H](O)[C@H](O)[C@H](O/C(C=O)=C\C([O-])=O)O[C@@H]1C([O-])=O.OC2[C@H](OC(O)C=O)[C@@H](C([O-])=O)O[C@@H](OC)[C@H]2O
reaction suitability:
__
Quality Level:
100
functional group:
__
storage temp.:
2-8°C
SMILES string:
CO[C@H]1[C@@H](O)[C@H](O)[C@H](O/C(C=O)=C\C([O-])=O)O[C@@H]1C([O-])=O.OC2[C@H](OC(O)C=O)[C@@H](C([O-])=O)O[C@@H](OC)[C@H]2O
reaction suitability: __
Quality Level: 100
functional group: __
storage temp.: 2-8°C
SMILES string: __
reaction suitability:
__
Quality Level:
100
functional group:
__
storage temp.:
2-8°C
SMILES string:
__