925144

KB05yne

≥95%

Manufacturer: Sigma Aldrich

Synonym(S): 4-(N-(4-Bromophenyl)acrylamido)-N-(hex-5-yn-1-yl)benzamide, Functionalized scout fragment

Select a Size

Pack Size SKU Availability Price
10 MG 925144-10-MG In Stock ₹ 23,440.00

925144 - 10 MG

₹ 23,440.00

In Stock

Quantity

1

Base Price: ₹ 23,440.00

GST (18%): ₹ 4,219.20

Total Price: ₹ 27,659.20

Quality Level

100

Assay

≥95%

form

powder or solid

reaction suitability

reagent type: chemical modification reagentreaction type: click chemistry

storage temp.

2-8°C

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Description

  • Application: KB05yne is a cysteine-reactive small-molecule fragment for chemoproteomic and ligandability studies for both traditionally druggable proteins as well as "undruggable," or difficult-to-target, proteins. This fragment electrophile is the functionalized version of KB02 (912131)Related useful products may include: Cysteine-reactive fragments: KB02 (912131), KB03 (912654), KB05 (911798), sulfoxide (925136), CoLDR probe (923818) Functionalized scout fragments: KB02-COOH (925047), KB02yne (925225) Electrophilic degraders featuring scout fragments: KB02-SLF (914738), KB03-SLF (914975), KB05-SLF (913715), Biotin-SLF (914223) Cysteine-reactive probes for chemoproteomics: IA alkyne (924237), IA 5-TAMRA (925020), desthiobiotin iodoacetamide (923826), or biotin iodoacetamide (B2059)Related useful products may include: Cysteine-reactive fragments: KB02 (912131), KB03 (912654), KB05 (911798), sulfoxide (925136), CoLDR probe (923818) Functionalized scout fragments: KB02-COOH (925047), KB02yne (925225) Electrophilic degraders featuring scout fragments: KB02-SLF (914738), KB03-SLF (914975), KB05-SLF (913715), Biotin-SLF (914223) Cysteine-reactive probes for chemoproteomics: IA alkyne (924237), IA 5-TAMRA (925020), desthiobiotin iodoacetamide (923826), or biotin iodoacetamide (B2059)Technology spotlight: Proteomic Ligandability Assessment
  • Other Notes: Functionalized Scout Fragments for Site-Specific Covalent Ligand Discovery and OptimizationElectrophilic PROTACs that degrade nuclear proteins by engaging DCAF16

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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