925225

KB02yne

Manufacturer: Sigma Aldrich

CAS Number: 2376152-06-4

Synonym(S): 2-Chloro-1-(6-(hex-5-yn-1-yloxy)-3,4-dihydroquinolin-1(2H)-yl)ethan-1-one, Functionalized scout fragment

Select a Size

Pack Size SKU Availability Price
10 MG 925225-10-MG In Stock ₹ 18,230.00

925225 - 10 MG

₹ 18,230.00

In Stock

Quantity

1

Base Price: ₹ 18,230.00

GST (18%): ₹ 3,281.40

Total Price: ₹ 21,511.40

form

powder or crystals (or Solid or Liquid)

Quality Level

100

reaction suitability

reagent type: chemical modification reagentreaction type: click chemistry

storage temp.

2-8°C

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Description

  • Application: KB02yne is a cysteine-reactive small-molecule fragment for chemoproteomic and ligandability studies for both traditionally druggable proteins as well as ″undruggable,″ or difficult-to-target, proteins. This fragment electrophile is the functionalized version of KB02 (912131).Related useful products may include:Cysteine-reactive fragments: KB02 (912131), KB03 (912654), KB05 (911798), sulfoxide (925136), CoLDR probe (923818)Functionalized scout fragments: KB02-COOH (925047), KB05yne (925144)Electrophilc degraders featuring scout fragments: KB02-SLF (914738), KB03-SLF (914975), KB05-SLF (913715), Biotin-SLF (914223)Cysteine-reactive probes for chemoproteomics: IA alkyne (924237), IA 5-TAMRA (925020), desthiobiotin iodoacetamide (923826), or biotin iodoacetamide (B2059)Technology spotlight: Proteomic Ligandability Assessment
  • Other Notes: Functionalized Scout Fragments for Site-Specific Covalent Ligand Discovery and OptimizationThe Proteome-Wide Potential for Reversible Covalency at CysteineElectrophilic PROTACs that degrade nuclear proteins by engaging DCAF16

SAFETY INFORMATION

WGK

WGK 3

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