Description

• General description: Chloroform-d (Deuterochloroform, CDCl3), deuterated chloroform, is a 100% isotopically enriched NMR (Nuclear Magnetic Resonance) solvent. It is widely employed in high resolution NMR studies due to its high chemical and isotopic purity. Quantitaive infrared spectral investigations of carbon-deuterium stretching bands of chloroform-d in various organic solvents have been reported.[1][2] Raman difference spectroscopic studies of mixtures of chloroform-d and liquid chloroform have been conducted to evaluate frequency shifts in the in the ν1 and ν2 bands of CHCl3 and CDCl3.[3]
• Application: Diphenylpyrrole-Strapped Calix[4]pyrrole Extractant for the Fluoride and Chloride Anions.: This study describes the development and application of a diphenylpyrrole-strapped calix[4]pyrrole as an effective extractant for fluoride and chloride anions, using Chloroform-d as a key solvent in its synthesis (Jung Heo N et al., 2023). A simple protocol for determination of enantiopurity of amines using BINOL derivatives as chiral solvating agents via (1)H- and (19)F-NMR spectroscopic analysis.: This research outlines a protocol utilizing Chloroform-d for the NMR spectroscopic analysis of amines′ enantiopurity, highlighting its role in enhancing spectral quality and resolution (Chaudhary P et al., 2022). Thermal oxidation stability of different multi-element oleogels via (1)H NMR spectroscopy.: Investigates the thermal oxidation stability of various oleogels, using Chloroform-d in the spectroscopic analysis to assess stability parameters (Qiu H et al., 2022). Solvation of the Boc-Val-Phe-nPr peptide characterized by VCD spectroscopy and DFT calculations.: Explores solvation effects on a peptide′s structure, employing Chloroform-d as a solvent to determine its impact on peptide behavior in solution (Scholten K et al., 2022). A straightforward catalytic approach to obtain deuterated chloroform at room temperature.: Discusses a novel method for producing Chloroform-d at room temperature, showcasing its practical applications in spectroscopic analysis and chemical synthesis (Higuera-Padilla AR et al., 2020).
• Recommended products: Check out ChemisTwin®, our brand new online portal for identity confirmation and quantification of NMR spectra. Learn more or reach out to us for a free trial.