Hamilton™ PRP™-C18 Reversed-Phase HPLC Columns: Stainless Steel

Description

• Rigid stationary phase has excellent mechanical and thermal stability, does not experience shrinking or swelling, and is completely inert to most conditions commonly encountered in reversed-phase chromatography
• Benefits & Features pH stable from 1 to 14 Temperature stability above 100°C Unique bonding of C18 to a polymer support LC/MS applications, synthesized DNA, and small molecules Excellent durability (stable to any concentration of water or organic solvent) Custom hardware dimensions available Analytical and semi-prep/preparative guard columns available Hamilton PRP-C18 Column is a durable and effective column for general purpose HPLC and is especially well-suited for specialized applications in the clinical, pharmaceutical, environmental, food, forensics, and life sciences industries
• Advantages of PRP-C18 Polymeric Reversed-Phase Columns Reproducibility Hamilton PRP-C18 reversed-phase columns are ideal for applications that require a high degree of column-to-column and batch to batch consistency (e.g., quality assurance, clinical trials)
• Because of the unique polymer bonding of the C18 to the PS-DVB support, PRP-C18 columns maintain their performance characteristics longer than many traditional C8 or C18 silica columns
• While many column manufacturers rely on other sources for their raw silica support, Hamilton manufactures its PRP-C18 support, assuring a consistent supply of PRP-C18 columns
• Long Life (Excellent Durability) Hamilton PRP-C18 is a new column designed to provide high-efficiency reversed-phase separations over an extended column life in nearly any mobile phase or pH
• The rigid stationary phase has excellent mechanical and thermal stability (>100°C), is pressure stable up to 5,000 psi, is highly cross-linked to prevent shrinkage or swelling (common in other polymeric columns) and is completely inert to most conditions commonly encountered in reversed-phase chromatography
• The PRP-C18 demonstrates pH stability even after prolonged exposure to concentrated (1 molar) NaOH and H 2 SO 4 with no measurable deterioration in performance, making restoration to original performance readily achievable where it is not possible with traditional HPLC columns
• PRP-C18 columns last 3 to 4 times longer than silica-based columns under most conditions due to the chemical durability of the base support.