12-141-0

Tocris Bioscience™ SIB 1893

Manufacturer: Tocris Bioscience™

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Quantity

10 mg

Product Type

SIB 1893

Molecular Weight (g/mol)

195.26

Inhibitors

SIB 1893

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Description

  • SIB 1893 is an a highly selective non-competitive antagonist for the metabotropic glutamate mGlu5 receptor subtype; displays an IC50 value of 0.3 μM at hmGlu5, compared with > 100 μM at hmGlu1b, hmGlu2, hmGlu6, hmGlu7 and hmGlu8
  • Centrally active upon systemic administration in vivo
  • Positive allosteric modulator at mGlu4 receptors.

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