48-421-0

Tocris Bioscience™ BIX 02189

Manufacturer: Tocris Bioscience™

Select a Size

Pack Size SKU Availability Price
Each of 1 48-421-0-Each-of-1 In Stock ₹ 29,014.00

48-421-0 - Each of 1

₹ 29,014.00

In Stock

Quantity

1

Base Price: ₹ 29,014.00

GST (18%): ₹ 5,222.52

Total Price: ₹ 34,236.52

Purity

>98%

Product Type

BIX 02189

Inhibitors

BIX 02189

Quantity

10 mg

Molecular Weight (g/mol)

440.54

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Description

  • BIX 02189 is a selective MEK5 and ERK5 inhibitor (IC50 values are 1.5 and 59 nM respectively)
  • Inhibits sorbitol-induced ERK5 phosphorylation in HeLa cells
  • Selective for MEK5 and ERK5 over MEK1/2, ERK1/2 and a panel of 87 kinases
  • Induces apoptosis in acute myeloid leukemia tumor cells.