47-761-0

Tocris Bioscience™ BIRT 377

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 47-761-0-Each-of-1 In Stock ₹ 28,705.38

47-761-0 - Each of 1

₹ 28,705.38

In Stock

Quantity

1

Base Price: ₹ 28,705.38

GST (18%): ₹ 5,166.968

Total Price: ₹ 33,872.348

Purity

>98%

Product Type

BIRT 377

Inhibitors

BIRT 377

Quantity

10 mg

Molecular Weight (g/mol)

442.13

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Description

  • Potent negative allosteric modulator of LFA-1 (lymphocyte function-associated antigen-1) (Kd = 26 nM)
  • Binds to the I-domain of LFA-1
  • Reversibly inhibits LFA-1 mediated binding of SKW3 leukemia cells to ICAM-1
  • Inhibits superantigen (SEB)-induced IL-2 production from lymphocytes in vitro and attenuates the SEB-induced increase in IL-2 plasma levels in a mouse model in vivo
  • Orally available.

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Purity:
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10 mg

Molecular Weight (g/mol):
442.13

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