47-765-0
Tocris Bioscience™ BIRT 377
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 47-765-0-Each-of-1 | In Stock | ₹ 1,19,441.76 |
47-765-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,19,441.76
GST (18%): ₹ 21,499.517
Total Price: ₹ 1,40,941.277
Purity
>98%
Product Type
BIRT 377
Inhibitors
BIRT 377
Quantity
50 mg
Molecular Weight (g/mol)
442.13
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Description
- Potent negative allosteric modulator of LFA-1 (lymphocyte function-associated antigen-1) (Kd = 26 nM)
- Binds to the I-domain of LFA-1
- Reversibly inhibits LFA-1 mediated binding of SKW3 leukemia cells to ICAM-1
- Inhibits superantigen (SEB)-induced IL-2 production from lymphocytes in vitro and attenuates the SEB-induced increase in IL-2 plasma levels in a mouse model in vivo
- Orally available.
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