37-125-0R

Tocris Bioscience™ NU 7441

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 37-125-0R-Each-of-1 In Stock ₹ 1,20,211.80

37-125-0R - Each of 1

₹ 1,20,211.80

In Stock

Quantity

1

Base Price: ₹ 1,20,211.80

GST (18%): ₹ 21,638.124

Total Price: ₹ 1,41,849.924

Purity

>99%

Quantity

50 mg

Molecular Weight (g/mol)

413.49

Gene Alias

KU 57788

Product Type

NU 7441

Inhibitors

NU 7441

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Description

  • Potent and selective DNA-PK inhibitor (IC50 = 14 nM)
  • Selective for DNA-PK over a range of kinases including mTOR, PI 3-K, ATM and ATR
  • Potentiates the effects of doxorubicin (Cat
  • No
  • 2252) and etoposide (Cat
  • No
  • 1226) in vitro and etoposide in vivo
  • Also enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency 2 to 3-fold, and decreases nonhomologous end-joining (NHEJ) frequency ∽40%.

Compare Similar Items

Show Difference

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Fischer Scientific

37-125-0R

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Purity:
>99%

Quantity:
50 mg

Molecular Weight (g/mol):
413.49

Gene Alias:
KU 57788

Product Type:
NU 7441

Inhibitors:
NU 7441

Img

Invitrogen

37-130-0

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Purity:
__

Quantity:
100 μg

Molecular Weight (g/mol):
__

Gene Alias:
2E6; AI528527; antigen CD18; B-2 integrin; CD18; CD18 leukocyte adhesion molecule; CD18 subunit; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; complement receptor C3 subunit beta; integrin beta 2; integrin beta chain, beta 2; integrin beta-2; integrin subunit beta 2; integrin, beta 2; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit); integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2); integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); ITGB2; LAD; LCAMB; Leu-CAM receptor; leukocyte cell adhesion molecule CD18; leukocyte surface protein; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; Lfa1; LFA-1; lymphocyte function associated antigen 1; MAC-1; Mac-1 beta; macrophage antigen 1 (mac-1) beta subunit); macrophage antigen-1 beta; MF17; MFI7

Product Type:
Antibody

Inhibitors:
__

Img

Tocris Bioscience™

37-151-R

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Purity:
>98%

Quantity:
1 mg

Molecular Weight (g/mol):
307.26

Gene Alias:
__

Product Type:
Other Rho GTPase Compounds

Inhibitors:
Narciclasine

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MilliporeSigma™

37-156-525MG

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Purity:
≥83% by UV

Quantity:
25 mg

Molecular Weight (g/mol):
__

Gene Alias:
__

Product Type:
Guanylyl 5′-Imidodiphosphate, Tetralithium Salt

Inhibitors:
__