5545938
Tocris Bioscience™ NU 7441
Potent and selective DNA-PK inhibitor
Manufacturer: Fischer Scientific
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Purity
>99%
Product Type
NU 7441
Inhibitors
NU 7441
Gene Alias
KU 57788
Molecular Weight (g/mol)
413.49
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Description
- Potent and selective DNA-PK inhibitor (IC50 = 14 nM)
- Selective for DNA-PK over a range of kinases including mTOR, PI 3-K, ATM and ATR
- Potentiates the effects of doxorubicin (Cat
- No
- 2252) and etoposide (Cat
- No
- 1226) in vitro and etoposide in vivo
- Also enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency 2 to 3-fold, and decreases nonhomologous end-joining (NHEJ) frequency ∽40%.
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Purity: >99%
Product Type: NU 7441
Inhibitors: NU 7441
Gene Alias: KU 57788
Molecular Weight (g/mol): 413.49
Purity:
>99%
Product Type:
NU 7441
Inhibitors:
NU 7441
Gene Alias:
KU 57788
Molecular Weight (g/mol):
413.49
Purity: >99%
Product Type: NVP ADW 742
Inhibitors: NVP ADW 742
Gene Alias: __
Molecular Weight (g/mol): 453.58
Purity:
>99%
Product Type:
NVP ADW 742
Inhibitors:
NVP ADW 742
Gene Alias:
__
Molecular Weight (g/mol):
453.58
Purity: 98%
Product Type: OF 1
Inhibitors: OF 1
Gene Alias: __
Molecular Weight (g/mol): M.W. (Observed): 440.31
Purity:
98%
Product Type:
OF 1
Inhibitors:
OF 1
Gene Alias:
__
Molecular Weight (g/mol):
M.W. (Observed): 440.31
Purity: >98%
Product Type: ONO AE3 208
Inhibitors: ONO AE3 208
Gene Alias: __
Molecular Weight (g/mol): 404.43
Purity:
>98%
Product Type:
ONO AE3 208
Inhibitors:
ONO AE3 208
Gene Alias:
__
Molecular Weight (g/mol):
404.43