504750R
Tocris Bioscience™ PRT 4165
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 504750R-Each-of-1 | In Stock | ₹ 47,481.50 |
504750R - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Purity
>99%
Product Type
PRT 4165
Inhibitors
PRT 4165
Quantity
50 mg
Molecular Weight (g/mol)
235.24
Related Products
Description
- PRT 4165 is an inhibitor of Bmi1/Ring1A, subunits of the polycomb repressive complex 1 (PRC1); inhibits self-ubiquitination (IC50 = 3.9 μM) but does not increase cellular levels of either subunit
- Prevents Bmi1/Ring1A-mediated ubiquitination and drug-induced degradation of topoisomerase 2α (Top2α)
- Also shown to inhibit the in vitro E3 ubiquitin ligase activity of RNF2 and a Bmi1/RNF2 complex, inhibiting H2A/H2AX ubiquitination
- Blocks polycomb repressor complex (PRC) 1-mediated histone H2A ubiquitination in vitro .
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Purity: >99%
Product Type: PRT 4165
Inhibitors: PRT 4165
Quantity: 50 mg
Molecular Weight (g/mol): 235.24
Purity:
>99%
Product Type:
PRT 4165
Inhibitors:
PRT 4165
Quantity:
50 mg
Molecular Weight (g/mol):
235.24
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