51-341-0

Tocris Bioscience™ MRT 67307 dihydrochloride

Manufacturer: Tocris Bioscience™

CAS Number: 1781882-89-0

Select a Size

Pack Size SKU Availability Price
Each of 1 51-341-0-Each-of-1 In Stock ₹ 26,994.18

51-341-0 - Each of 1

₹ 26,994.18

In Stock

Quantity

1

Base Price: ₹ 26,994.18

GST (18%): ₹ 4,858.952

Total Price: ₹ 31,853.132

Purity

>98%

Quantity

10 mg

Molecular Weight (g/mol)

537.52

CAS

1781882-89-0

Product Type

MRT 67307 dihydrochloride

Inhibitors

MRT 67307 dihydrochloride

Other Options

Image Product Name Manufacturer Price Range
AR020AYI
MRT67307 HCl
Aaron Chemicals LLC ₹ 3,764.64 - ₹ 3,22,561.20

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Description

  • MRT 67307 dihydrochloride is a salt inducible kinase (SIK) inhibitor (IC50 values are 67, 250 and 430 nM for SIK2, SIK1 and SIK3 respectively)
  • Also inhibits TBK1, MARK1-4, IKKε and NUAK1 (IC50 values are 19, 27-52, 160 and 230 nM respectively)
  • Has no effect on IKKα or IKKβ
  • Induces IL-10 secretion and inhibits TNF-α and IL-6 secretion in bacterial LPS-stimulated macrophages
  • Also enhances IL-1-induced activation of NFκB-dependent gene transcription in mouse embryonic fibroblast (MEF) cells
  • Inhibits autophagy.

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>98%

Quantity:
10 mg

Molecular Weight (g/mol):
537.52

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1781882-89-0

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Inhibitors:
MRT 67307 dihydrochloride

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Molecular Weight (g/mol):
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