5545798
Tocris Bioscience™ FR 180204
Selective ERK inhibitor
Manufacturer: Fischer Scientific
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Purity
>98%
Product Type
FR 180204
Molecular Weight (g/mol)
327.34
Inhibitors
FR 180204
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Description
- Selective ERK inhibitor (IC50 values are 0.14 and 0.31 μM for ERK2 and ERK1 respectively)
- Displays 30-fold selectivity for ERK over p38α (IC50 = 10 μM); displays no activity against human recombinant MEK1, MKK4, IKKα, PKCα, Src, Syc and PDGFα at concentrations less than 30 μM
- Also inhibits TGFβ-induced AP-1 activation in Mv1Lu cells (IC50 = 3.1 μM).
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Purity: >98%
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Molecular Weight (g/mol): 327.34
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Molecular Weight (g/mol):
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Molecular Weight (g/mol): 532.57
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Molecular Weight (g/mol):
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