5546110

Tocris Bioscience™ XAP 044

Potent and selective mGlu7 antagonist

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Purity

>98%

Product Type

XAP 044

Molecular Weight (g/mol)

380.13

Inhibitors

XAP 044

Related Products

Img

Fischer Scientific

52-481-0

--

Img

Fischer Scientific

52-485-0

--

Img

Fischer Scientific

5545798

Selective ERK inhibitor...

Img

Tocris Bioscience™

47-011-0

--

Img

Fischer Scientific

5545713

Potent negative allosteric modulato...

Img

Fischer Scientific

5546007

ATP citrate lyase (ACLY) inhibitor...

Img

Tocris Bioscience™

21-725-0

--

Img

Fischer Scientific

47-761-0

--

Description

  • Potent and selective mGlu7 antagonist (IC50 = 88 nM); inhibits lateral amygdala long term potentiation (LTP) in brain slices from wild type mice
  • Displays no effects on the LTP of mGlu7 deficient mice
  • Exhibits novel activity by binding to the mGlu7 Venus flytrap domain (VFTD)
  • Exhibits anti-anxiety effects in rodent models
  • Brain penetrant.

Compare Similar Items

Show Difference

Img

Fischer Scientific

5546110

Potent and selective mGlu7 antagoni...


Purity:
>98%

Product Type:
XAP 044

Molecular Weight (g/mol):
380.13

Inhibitors:
XAP 044

Img

Fischer Scientific

5546116

Broad spectrum steroid receptor lig...


Purity:
>98%

Product Type:
Z-Guggulsterone

Molecular Weight (g/mol):
312.45

Inhibitors:
Z-Guggulsterone

Img

Fischer Scientific

5546123

PFKFB3 inhibitor...


Purity:
>99%

Product Type:
3PO

Molecular Weight (g/mol):
210.23

Inhibitors:
3PO

Img

Fischer Scientific

5546126

High affinity Smurf1 inhibitor; enh...


Purity:
>98%

Product Type:
A01

Molecular Weight (g/mol):
512.93

Inhibitors:
A01