5545808
Tocris Bioscience™ GSK 1562590 hydrochloride
High affinity, selective urotensin II (UT) receptor antagonist
Manufacturer: Fischer Scientific
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Purity
>98%
Product Type
GSK 1562590 hydrochloride
Molecular Weight (g/mol)
617.95
Inhibitors
GSK 1562590 hydrochloride
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Description
- High affinity and selective urotensin II (UT) receptor antagonist (pKi values are 9.14, 9.28, 9.34, 9.64 and 9.66 at monkey, human, mouse, cat and rat recombinant receptors respectively)
- Exhibits selectivity for UT receptors over a range of GPCRs, ion channels, enzymes and neurotransmitter transporters
- Supresses human urotensin-II (hU-II)-induced contraction of isolated rat aorta in vitro and ex vivo
- Inhibits the hU-II-induced increase in mean blood pressure in vivo
- Orally active.
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Purity: >98%
Product Type: GSK 1562590 hydrochloride
Molecular Weight (g/mol): 617.95
Inhibitors: GSK 1562590 hydrochloride
Purity:
>98%
Product Type:
GSK 1562590 hydrochloride
Molecular Weight (g/mol):
617.95
Inhibitors:
GSK 1562590 hydrochloride
Purity: >98%
Product Type: GSK 1838705
Molecular Weight (g/mol): 532.57
Inhibitors: GSK 1838705
Purity:
>98%
Product Type:
GSK 1838705
Molecular Weight (g/mol):
532.57
Inhibitors:
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Purity: >97%
Product Type: GSK 429286
Molecular Weight (g/mol): 432.37
Inhibitors: GSK 429286
Purity:
>97%
Product Type:
GSK 429286
Molecular Weight (g/mol):
432.37
Inhibitors:
GSK 429286
Purity: __
Product Type: GYY 4137 morpholine salt
Molecular Weight (g/mol): 376.47
Inhibitors: GYY 4137 morpholine salt
Purity:
__
Product Type:
GYY 4137 morpholine salt
Molecular Weight (g/mol):
376.47
Inhibitors:
GYY 4137 morpholine salt