5545947

Tocris Bioscience™ OXF BD 02

Selective BRD4(1) inhibitor

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Purity

>98%

Product Type

OXF BD 02

Molecular Weight (g/mol)

295.33

Inhibitors

OXF BD 02

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Description

  • Selective inhibitor of the first bromodomain of BRD4 (BRD4(1)) (IC50 = 382 nM)
  • Exhibits 2-3-fold selectivity for BRD4(1) over the CBP bromodomain and has little affinity for a range of other bromodomains
  • Reduces viability of lung adenocarcinoma cell lines and attenuates proliferation of MV-4-11 leukemia cells
  • Cell permeable.

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Inhibitors:
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