5545982

Tocris Bioscience™ Pyridostatin pentahydrochloride

Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest

Manufacturer: Fischer Scientific

CAS Number: 1781882-65-2

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CAS

1781882-65-2

Product Type

Pyridostatin pentahydrochloride

Inhibitors

Pyridostatin pentahydrochloride

Other Options

Image Product Name Manufacturer Price Range
50-245-7459
eMolecules​ Medchem Express / Pyridostatin (hydrochloride) / 5mg / 446265082 / HY-15176A / / 1781882-65-2 / MFCD28133372 / 778.940 / C31H37Cl5N8O5
eMolecules​ ₹ 13,349.93
47-631-0
Tocris Bioscience™ Pyridostatin pentahydrochloride
Fischer Scientific ₹ 29,304.30
47-635-0
Tocris Bioscience™ Pyridostatin pentahydrochloride
Fischer Scientific --
AX64618
1781882-65-2 | Pyridostatin hydrochloride
A2B Chem ₹ 12,063.96 - ₹ 78,629.64

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Description

  • Binds and stabilizes G-quadruplexes, inducing DNA damage and cell cycle arrest (Kd = 490 nM); targets the proto-oncogene Src, reducing Src protein abundance and Src-dependent motility in human breast cancer cells
  • Also targets telomeric G-quadruplexes, inducing telomerase dysfunction
  • Activates the DNA-dependent protein kinase catalytic sunbunit (DNA-PKcs).

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