BDB556472

BD Caspase-3

Manufacturer: BD

The price for this product is unavailable. Please request a quote

Concentration

0.2mg/mL

Formulation

50mM Tris (pH 8) with 100mM NaCl and 50mM Imidazole

Quantity

5μg

Cross Reactivity

Human

Form

Purified

For Use With (Application)

Enzyme Assay

Name

Human Caspase-3 Active Form Recombinant Protein

Storage Requirements

-80°C

Recombinant

Recombinant

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Description

  • Caspases are cysteine proteases that play central role in apoptosis
  • The caspase family was discovered by searching human cDNA libraries for sequences homologous to ced-3, a C
  • Each caspase is synthesized as an inactive proenzyme that is processed by cleavage at asparte residues by another protease or by self-proteolysis
  • Fas and tumor necrosis factor receptor type 1 (TNFR1) One of their substrates is poly (ADP ribose) polymerase (PARP) Cleave PARP from its 116kDa form to 85kDa residual fragment The cleavage site in PARP is C-terminal to Asp-216 Utilized as basis for highly specific caspase-3 substrates such as Ac(N-acetyl)-DEVD-AFC (7-amino-4-trifluoromethylcourmarin) and Ac(N-acetyl)-DEVD-AMC (7-amino-4-methylcoumarin) as well as caspase-3 aldehyde inhibitor Ac-DEVD-CHO Storage Buffer: 50mM Tris (pH 8.0) with 100mM NaCl and 50mM imidazole Format: Purified

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BDB556472

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Concentration:
0.2mg/mL

Formulation:
50mM Tris (pH 8) with 100mM NaCl and 50mM Imidazole

Quantity:
5μg

Cross Reactivity:
Human

Form:
Purified

For Use With (Application):
Enzyme Assay

Name:
Human Caspase-3 Active Form Recombinant Protein

Storage Requirements:
-80°C

Recombinant:
Recombinant

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Recombinant:
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