Thermo Scientific™ Novobiocin Disk

Description

• Differentiate Staphylococcus saprophyticus from other coagulase-negative staphylococci with Thermo Scientific™ Remel™ Novobiocin Disk
• In 1975, Kloos and Schleifer 1 introduced the novobiocin disk test
• Further studies were then conducted in 1977 using the novobiocin disk test for presumptive identification of S
• saprophyticus, isolated from the clinical specimens 2,3,4
• Novobiocin Disk can be used to differentiate S
• saprophyticus from other coagulase-negative staphylococci by overnight disk test method or 5-hour broth disk procedure
• In 1984, Harrington and Gaydos 5 , compared these methods
• Staphylococcus saprophyticus is a common cause of urinary tract infections in female patients
• This understanding has led to exploring several methods to identify this pathogen in clinical specimens
• Ready to use : Reagent-impregnated disk
• Convenient: Can be used for the overnight disk test method or the 5-hour broth disk procedure Easy to interpret: Visual inspection to observe turbidity or growth
• The Novobiocin Disk contains 5 μg novobiocin
• Novobiocin resistance is intrinsic in S
• saprophyticus
• The mechanisms of novobiocin resistance include inhibition of cell wall synthesis as well as protein and nucleic acid synthesis
• The Novobiocin Disk can therefore be used to differentiate S
• saprophyticus from other coagulase-negative staphylococci
• The disks can be used for testing by the overnight disk method or the 5-hour broth disk procedure
• Not all products are available for sale in all territories
• Please inquire
• Remel™ and Oxoid™ products are now part of the Thermo Scientific brand.