4817302

QIAGEN QIAcard FTA DMPK

For collection, stabilization, processing, transport and archiving of biological samples. 4 sample areas per card.

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Format

Card

For Use With (Application)

For protein-based biomolecules, on-substrate cleanup has potential to convey greater analyte stability, requires fewer experimental animals

Includes

100 cards

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Description

  • For collection, stabilization, processing, transport and archiving of biological samples
  • 4 sample areas per card
  • QIAcard FTA DMPK Cards for Drug Metabolism Pharmacokinetic enable microvolume sampling with only 10 to 20 μL per sample and are designed for use with blood samples
  • The cards can also be used with colorless samples such as plasma, cerebrospinal fluid and urine
  • QIAcard FTA DMPK-A and QIAcard FTA DMPK-B contains impregnated chemicals enabling protein denaturation to inactivate endogenous enzymes
  • Cell lysis releases endogenous cellular materials onto card
  • Stabilization of DNA allows resampling of blood spot for pharmacogenomics.Impregnated chemicals may interfere with mass spectrometry detection (e.g
  • ion suppression)
  • QIAcard FTA DMPK-C contain pure cellulose
  • No impregnated chemicals to interfere with analysis
  • Proteins are not denatured so cards may be better suited for protein based biomolecules and antibody studies
  • Analysis: Analysis primarily with HPLC or UHPLC followed by MS/MS detection, direct desorption MS techniques such as DESI
  • Methanol or aqueous/organic mixtures have been shown to work well for small molecules and aqueous buffers are recommended for proteins
  • Select a good solvent for the analyte while maintaining compatibility with the HPLC conditions to be used
  • The choice of DMPK card depends on many factors such as the analyte chemical structure, extraction solvent and analysis workflow.

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