200006966

Tocris Bioscience™ 5-Ph-IAA-AM

Selective and potent TAG Degrader for auxin-inducible degron 2 system; 5-Ph-IAA analog

Manufacturer: Fischer Scientific

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Chemical Name or Material

Acetoxymethyl 2-(5-phenyl-1H-indol-3-yl)acetate

Target

TAG Degradation Platforms

Molecular Formula

C19H17NO4

Purity

0.98

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Description

  • 5-Ph-IAA-AM is a potent and selective "Bump & Hole" TAG Degrader, for use within an auxin-inducible degron (AID2) system; it is an egg-permeant analog of 5-Ph-IAA (Cat
  • No
  • 7392)
  • 5-Ph-IAA-AM induces selective degradation of a target protein tagged with a single-point mutant AtTIR1F79G F-box protein
  • 5-Ph-IAA-AM induces target protein degradation in C
  • elegans embryos
  • No developmental abnormality is observed when the embryos are treated with 50 μM 5-Ph-IAA-AM.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Chemical Name or Material:
Acetoxymethyl 2-(5-phenyl-1H-indol-3-yl)acetate

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