518510

Tocris Bioscience™ JTE 607 Dihydrochloride

Manufacturer: Fischer Scientific

CAS Number: 188791-09-5

Select a Size

Pack Size SKU Availability Price
Each of 1 518510-Each-of-1 In Stock ₹ 34,754.50

518510 - Each of 1

₹ 34,754.50

In Stock

Quantity

1

Base Price: ₹ 34,754.50

GST (18%): ₹ 6,255.81

Total Price: ₹ 41,010.31

Chemical Name or Material

JTE 607 dihydrochloride

Synonym

N-[3,5-Dichloro-2-hydroxy-4-[2-(4-methyl-1-piperazinyl)ethoxy]benzoyl]-L-phenylalanine ethyl ester dihydrochloride

Solubility

Soluble to 100mM in water and to 100mM in DMSO

Formula Weight

597.36

Product Type

Bioactive Small Molecule

CAS

188791-09-5

Quantity

10 mg

Molecular Formula

C25H31Cl2N3O5·2HCl

Physical Form

Solid

Purity

>98%

Other Options

Image Product Name Manufacturer Price Range
Tocris Bioscience™ JTE 607 Dihydrochloride
-- --
Tocris Bioscience™ JTE 607 Dihydrochloride
-- ₹ 1,45,159.00
Medchemexpress LLC HY-110133 10mg , JTE-607 CAS:188791-09-5 Purity:>98%
-- ₹ 18,503.10
eMolecules​ Medchem Express / JTE-607 / 5mg / 686240174 / HY-110133 / / 188791-09-5 / MFCD07363998 / 597.360 / C25H33Cl4N3O5
-- ₹ 14,410.88
188791-09-5 | JTE607Dihydrochloride
-- ₹ 7,209.00 - ₹ 74,315.00

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Description

  • Cytokine release inhibitor
  • Inhibits production of IL-1β, IL-8, IL-6, IL-10 and TNFα (IC50 values are 5.9, 7.3, 8.8, 9.1 and 11.0 nM, respectively) from LPS-stimulated PBMCs
  • Reduces proinflammatory cytokine-release and attenuates lung permeability in a rat lung injury model
  • Induces apoptosis in leukemia cells in vitro and prolongs survival in a mouse leukemia model.

SAFETY INFORMATION

  • Recommended Storage : Desiccate at Room Temperature