563610

Tocris Bioscience™ GS 143

Manufacturer: Fischer Scientific

CAS Number: 916232-21-8

Select a Size

Pack Size SKU Availability Price
Each of 1 563610-Each-of-1 In Stock ₹ 23,058.42

563610 - Each of 1

₹ 23,058.42

In Stock

Quantity

1

Base Price: ₹ 23,058.42

GST (18%): ₹ 4,150.516

Total Price: ₹ 27,208.936

Chemical Name or Material

4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]benzoic acid

Quantity

10 mg

Molecular Formula

C28H19FN2O4

Purity

>98%

CAS

916232-21-8

Target

Ubiquitin Ligase (E3) Inhibitors

Formula Weight

466.46

Other Options

Image Product Name Manufacturer Price Range
7110855
Tocris Bioscience™ GS 143
Fischer Scientific --
563650
Tocris Bioscience™ GS 143
Fischer Scientific ₹ 96,255.00
50-245-2739
eMolecules​ Medchem Express / GS143 / 5mg / 552386433 / HY-110261 / / 916232-21-8 / MFCD30182334 / 466.468 / C28H19FN2O4
eMolecules​ ₹ 13,853.88
AW10115
916232-21-8 | 4-(3-Benzyl-4-{[5-(2-fluorophenyl)furan-2-yl]methylidene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid
A2B Chem ₹ 8,213.76 - ₹ 12,919.56

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Description

  • β-TrCP1 ligase inhibitor
  • Inhibits IκBα ubiquitination (IC50 = 5.2 μM) without affecting proteasome activity
  • Blocks LPS-induced expression of inflammatory cytokines in human myelomonocytic cells
  • Suppresses antigen-induced NFκB expression, inflammation and mucus production in airways of OVA-sensitized mice.

SAFETY INFORMATION

  • Recommended Storage : Store at 4°C

Compare Similar Items

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Img

Fischer Scientific

563610

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Chemical Name or Material:
4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]benzoic acid

Quantity:
10 mg

Molecular Formula:
C28H19FN2O4

Purity:
>98%

CAS:
916232-21-8

Target:
Ubiquitin Ligase (E3) Inhibitors

Formula Weight:
466.46

Img

Fischer Scientific

563650

--


Chemical Name or Material:
4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]benzoic acid

Quantity:
50 mg

Molecular Formula:
C28H19FN2O4

Purity:
>98%

CAS:
916232-21-8

Target:
Ubiquitin Ligase (E3) Inhibitors

Formula Weight:
466.46

Img

Sigma Aldrich

563676

0.5 M in THF...


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Sigma Aldrich

563722

0.5 M in THF...


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