563650

Tocris Bioscience™ GS 143

Manufacturer: Fischer Scientific

CAS Number: 916232-21-8

Select a Size

Pack Size SKU Availability Price
Each of 1 563650-Each-of-1 In Stock ₹ 1,00,125.00

563650 - Each of 1

₹ 1,00,125.00

In Stock

Quantity

1

Base Price: ₹ 1,00,125.00

GST (18%): ₹ 18,022.50

Total Price: ₹ 1,18,147.50

Chemical Name or Material

4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]benzoic acid

Quantity

50 mg

Molecular Formula

C28H19FN2O4

Purity

>98%

CAS

916232-21-8

Target

Ubiquitin Ligase (E3) Inhibitors

Formula Weight

466.46

Other Options

Image Product Name Manufacturer Price Range
Tocris Bioscience™ GS 143
-- --
Tocris Bioscience™ GS 143
-- ₹ 23,985.50
eMolecules​ Medchem Express / GS143 / 5mg / 552386433 / HY-110261 / / 916232-21-8 / MFCD30182334 / 466.468 / C28H19FN2O4
-- ₹ 14,410.88
916232-21-8 | 4-(3-Benzyl-4-{[5-(2-fluorophenyl)furan-2-yl]methylidene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid
-- ₹ 8,544.00 - ₹ 13,439.00

Related Products

Img

Fischer Scientific

563610

--

Img

Fischer Scientific

7110855

β-TrCP1 ligase inhibitor...

Img

Fischer Scientific

69-655-0

--

Img

Fischer Scientific

56-465-0

--

Img

Fischer Scientific

69-651-0

--

Img

Fischer Scientific

67-915

--

Img

Fischer Scientific

56-461-0

--

Img

Fischer Scientific

67-912-5

--

Description

  • β-TrCP1 ligase inhibitor
  • Inhibits IκBα ubiquitination (IC50 = 5.2 μM) without affecting proteasome activity
  • Blocks LPS-induced expression of inflammatory cytokines in human myelomonocytic cells
  • Suppresses antigen-induced NFκB expression, inflammation and mucus production in airways of OVA-sensitized mice.

SAFETY INFORMATION

  • Recommended Storage : Store at 4°C