58-035-0

Tocris Bioscience™ MP A08

Manufacturer: Tocris Bioscience™

CAS Number: 219832-49-2

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Chemical Name or Material

4-Methyl-N-[2-[[[2-[[(4-methylphenyl)sulfonyl]amino]phenyl]imino]methyl]phenyl]benzenesulfonamide

Synonym

NSC 122314

Molecular Formula

C27H25N3O4S2

CAS

219832-49-2

Quantity

50 mg

Formula Weight

519.64

Other Options

Image Product Name Manufacturer Price Range
50-208-2186
Medchemexpress LLC HY-19794 5mg Medchemexpress, MP-A08 CAS:219832-49-2 Purity:>98%
Medchemexpress LLC ₹ 4,941.09
50-249-1093
eMolecules​ Medchem Express / MP-A08 / 1mg / 446270349 / HY-19794 / / 219832-49-2 / MFCD01053753 / 519.630 / C27H25N3O4S2
eMolecules​ ₹ 4,606.55
AF32733
219832-49-2 | Mp-a08
A2B Chem ₹ 2,566.80 - ₹ 30,544.92

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Description

  • MP A08 is a selective ATP competitive sphingosine kinase 2 and 1 (SphK2/1) inhibitor (Ki values are 6.9 and 27 μM, respectively)
  • Exhibits selectivity for SphK 1 and 2 over other kinases
  • Inhibits cellular S1P production and increases sphingosine and ceramide levels in vitro
  • Also induces mitochondrial-associated apoptosis
  • Reduces tumor growth in a human lung adenocarcinoma xenograft mouse model, by inducing apoptosis and suppressing angiogenesis
  • Cell permeable.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Chemical Name or Material:
4-Methyl-N-[2-[[[2-[[(4-methylphenyl)sulfonyl]amino]phenyl]imino]methyl]phenyl]benzenesulfonamide

Synonym:
NSC 122314

Molecular Formula:
C27H25N3O4S2

CAS:
219832-49-2

Quantity:
50 mg

Formula Weight:
519.64

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