59-271-0

Tocris Bioscience™ NS 383

Manufacturer: Fischer Scientific

CAS Number: 309711-59-9

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Pack Size SKU Availability Price
Each of 1 59-271-0-Each-of-1 In Stock ₹ 15,482.94

59-271-0 - Each of 1

₹ 15,482.94

In Stock

Quantity

1

Base Price: ₹ 15,482.94

GST (18%): ₹ 2,786.929

Total Price: ₹ 18,269.869

Chemical Name or Material

8-Ethyl-6,7,8,9-tetrahydro-5-phenyl-1 H-pyrrolo[3,2-h]isoquinoline-2,3-dione-3-oxime

Quantity

10 mg

Molecular Formula

C19H19N3O2

CAS

309711-59-9

Target

Acid-sensing Ion Channel Blockers

Other Options

Image Product Name Manufacturer Price Range
7237097
Tocris Bioscience™ NS 383
Fischer Scientific --
59-275-0
Tocris Bioscience™ NS 383
Fischer Scientific ₹ 64,512.24

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Description

  • NS 383 is an ASIC blocker (IC50 values are 0.44, 2.1 μM and no effect at rat ASIC1a, ASIC3 and ASIC2a, respectively: IC50 value = 0.12 μM at human ASIC1a with no effect at ASIC2a or ASIC3)
  • Inhibition was also observed at heteromeric ASIC channels (IC50 values are 0.79, 0.87 and 4.5 uM at rat ASIC1a+3, ASIC1a+2a and ASIC2a+3; IC5O values are 0.33 and 0.69 uM at human ASIC1a+2a and ASIC1a+3, with no effect at ASIC2a+3)
  • Attenuates pathophysiological nociceptive behaviors in CFA-inflamed and CCI rats.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

Compare Similar Items

Show Difference

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Fischer Scientific

59-271-0

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Chemical Name or Material:
8-Ethyl-6,7,8,9-tetrahydro-5-phenyl-1 H-pyrrolo[3,2-h]isoquinoline-2,3-dione-3-oxime

Quantity:
10 mg

Molecular Formula:
C19H19N3O2

CAS:
309711-59-9

Target:
Acid-sensing Ion Channel Blockers

Img

Fischer Scientific

59-275-0

--


Chemical Name or Material:
8-Ethyl-6,7,8,9-tetrahydro-5-phenyl-1 H-pyrrolo[3,2-h]isoquinoline-2,3-dione-3-oxime

Quantity:
50 mg

Molecular Formula:
C19H19N3O2

CAS:
309711-59-9

Target:
Acid-sensing Ion Channel Blockers

Img

Fischer Scientific

59-311-0

--


Chemical Name or Material:
4-[2-(3-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-4-thiazolylbenzenesulfonamide tosylate

Quantity:
10 mg

Molecular Formula:
C18H12Cl2FN5O3S2.C7H8O3S

CAS:
1430806-04-4

Target:
Voltage-gated Sodium Channel Blockers

Img

Fischer Scientific

59-315-0

--


Chemical Name or Material:
4-[2-(3-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-4-thiazolylbenzenesulfonamide tosylate

Quantity:
50 mg

Molecular Formula:
C18H12Cl2FN5O3S2.C7H8O3S

CAS:
1430806-04-4

Target:
Voltage-gated Sodium Channel Blockers