61-802-5

NMS 873

Manufacturer: Fischer Scientific

CAS Number: 1418013-75-8

Select a Size

Pack Size SKU Availability Price
Each of 1 61-802-5-Each-of-1 In Stock ₹ 45,817.38

61-802-5 - Each of 1

₹ 45,817.38

In Stock

Quantity

1

Base Price: ₹ 45,817.38

GST (18%): ₹ 8,247.128

Total Price: ₹ 54,064.508

Chemical Name or Material

3-[3-(Cyclopentylthio)-5-[[[2-methyl-4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]oxy]methyl]-4H-1,2,4-triazol-4-yl]pyridine

Assay Percent Range

>98%

Molecular Formula

C27H28N4O3S2

CAS

1418013-75-8

Quantity

25 mg

Formula Weight

Observed MW: 520.67

Other Options

Image Product Name Manufacturer Price Range
7116107
NMS 873
Fischer Scientific --
61-805-RD
NMS 873
Fischer Scientific ₹ 12,235.08
50-244-9524
eMolecules​ Medchem Express / NMS-873 / 5mg / 446266412 / HY-15713 / / 1418013-75-8 / MFCD28009371 / 520.670 / C27H28N4O3S2
eMolecules​ ₹ 9,824.00
50-101-5294
Apexbio Technology LLC allosteric and specific p97 inhibitor 1418013-75-8. MFCD28009371
Apexbio Technology LLC ₹ 5,818.08
50-173-7707
Sigma Aldrich Fine Chemicals Biosciences NMS-873 >=98% (HPLC) | 1418013-75-8 | MFCD28009371 | 25MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 61,687.05
50-1737-708
Sigma Aldrich Fine Chemicals Biosciences NMS-873 >=98% (HPLC) | 1418013-75-8 | MFCD28009371 | 5MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 16,875.00

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Description

  • Potent p97 ATPase (VCP) allosteric inhibitor (IC50 = 30 nM)
  • Selective over all other AAA ATPases, HSP90 and kinases tested (IC50 >10 μM)
  • Activates the unfolded protein response (UPR) and modulates autophagosome maturation
  • Exhibits antiproliferative activity in cancer cells in vitro (IC50 values are 400 and 700 nM for HCT116 and HeLa cells respectively)
  • Reduces p97-sensitization to trypsin digestion.

SAFETY INFORMATION

  • Recommended Storage : Store at 4°C

Compare Similar Items

Show Difference

Img

Fischer Scientific

61-802-5

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Chemical Name or Material:
3-[3-(Cyclopentylthio)-5-[[[2-methyl-4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]oxy]methyl]-4H-1,2,4-triazol-4-yl]pyridine

Assay Percent Range:
>98%

Molecular Formula:
C27H28N4O3S2

CAS:
1418013-75-8

Quantity:
25 mg

Formula Weight:
Observed MW: 520.67

Img

Fischer Scientific

61-805-RD

--


Chemical Name or Material:
3-[3-(Cyclopentylthio)-5-[[[2-methyl-4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]oxy]methyl]-4H-1,2,4-triazol-4-yl]pyridine

Assay Percent Range:
>98%

Molecular Formula:
C27H28N4O3S2

CAS:
1418013-75-8

Quantity:
5 mg

Formula Weight:
Observed MW: 520.67

Img

Fischer Scientific

61-821-0

--


Chemical Name or Material:
α-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol

Assay Percent Range:
>98%

Molecular Formula:
C11H18N4O3

CAS:
70132-50-2

Quantity:
10 mg

Formula Weight:
Observed MW: 254.29

Img

Fischer Scientific

61-825-0

--


Chemical Name or Material:
α-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol

Assay Percent Range:
>98%

Molecular Formula:
C11H18N4O3

CAS:
70132-50-2

Quantity:
50 mg

Formula Weight:
Observed MW: 254.29