64-991-0
Tocris Bioscience™ MLN 4924
Manufacturer: Fischer Scientific
CAS Number: 905579-51-3
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 64-991-0-Each-of-1 | In Stock | ₹ 18,138.72 |
64-991-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 18,138.72
GST (18%): ₹ 3,264.97
Total Price: ₹ 21,403.69
Chemical Name or Material
[(1 S,2 S,4 R)-4-[4-[[(1 S)-2,3-Dihydro-1 H-inden-1-yl]amino]-7 H-pyrrolo[2,3-d]pyrimidin-7-yl]-2-hydroxycyclopentyl]methyl sulfamic acid ester
Quantity
10 mg
Molecular Formula
C21H25N5O4S
CAS
905579-51-3
Target
NEDD8 Activating Enzyme E1)
Purity
0.98
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ MLN 4924 | Fischer Scientific | -- | |
| | Tocris Bioscience™ MLN 4924 | Fischer Scientific | ₹ 75,763.38 | |
 | Apexbio Technology LLC MLN4924, 10mg. Cas: 905579-51-3 MFCD: MFCD17215201. NAE inhibitor | Apexbio Technology LLC | ₹ 19,764.36 | |
| | Apexbio Technology LLC MLN4924, 50mg. Cas: 905579-51-3 MFCD: MFCD17215201. NAE inhibitor | Apexbio Technology LLC | ₹ 49,624.80 | |
 | Ubpbio A cell-permeable and irreversible inhibitor of Nedd8-activating enzyme (NAE), CAS# 905579-51-3, >98% purity | Ubpbio | ₹ 13,775.16 | |
 | Medchemexpress LLC HY-70062 1mg , Pevonedistat CAS:905579-51-3 Purity:>98% | Medchemexpress LLC | ₹ 5,390.28 | |
 | Selleck Chemical LLC Pevonedistat (MLN4924) 2mg 905579-51-3 | Selleck Chemical LLC | ₹ 15,092.78 | |
| | Cayman Chemical Pevonedistat | 905579-51-3 | 443.5 g/mol | 10MG | Cayman Chemical | ₹ 16,530.19 | |
 | Chemie Tek MLN4924 (PEVONEDISTAT), 905579-51-3, MFCD17215201, 5mg | Chemie Tek | ₹ 6,844.80 | |
 | Cayman Chemical MLN4924, 905579-51-3, 1 mg | Cayman Chemical | ₹ 4,894.03 |
Related Products
Description
- MLN 4924 (Tak 924) is a potent and selective NEDD8 activating enzyme (NAE) inhibitor (IC50 = 4.7 nM)
- MLN 4924 exhibits selectivity over closely related enzymes UAE, UBA6, SAE, and ATG7 (IC50 = 1.5, 1.8, 8.2, and >10 μM, respectively), and displays minimal activity at adenosine receptors and a panel of 12 cellular kinases
- MLN 4924 exhibits cyotoxicity in several human tumor-derived cell lines and causes liver damage in SD rats, when given with TNF-α
- It blocks the NEDD8 pathway causing DNA damage in mice bearing HCT-116 xenografts
- Cell permeable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: [(1 S,2 S,4 R)-4-[4-[[(1 S)-2,3-Dihydro-1 H-inden-1-yl]amino]-7 H-pyrrolo[2,3-d]pyrimidin-7-yl]-2-hydroxycyclopentyl]methyl sulfamic acid ester
Quantity: 10 mg
Molecular Formula: C21H25N5O4S
CAS: 905579-51-3
Target: NEDD8 Activating Enzyme E1)
Purity: 0.98
Chemical Name or Material:
[(1 S,2 S,4 R)-4-[4-[[(1 S)-2,3-Dihydro-1 H-inden-1-yl]amino]-7 H-pyrrolo[2,3-d]pyrimidin-7-yl]-2-hydroxycyclopentyl]methyl sulfamic acid ester
Quantity:
10 mg
Molecular Formula:
C21H25N5O4S
CAS:
905579-51-3
Target:
NEDD8 Activating Enzyme E1)
Purity:
0.98
Chemical Name or Material: __
Quantity: 100 Tests
Molecular Formula: __
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